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242667 Dlgap3

242667

Dlgap3

DLG associated protein 3

protein-coding

Mus musculus

基因描述

Type Description
Definition DLG associated protein 3

研究结论

Date Results Publications
2021-01-16 15:57:00 Instrumental learning in a mouse model for obsessive-compulsive disorder: Impaired habit formation in Sapap3 mutants. 31927083
2020-04-04 13:04:00 studies are among the first to describe cognitive impairments in a transgenic Obsessive Compulsive Disorder -relevant model, and demonstrate pronounced heterogeneity among Sapap3-Knockouts. These findings suggest that increased neural activity in m Prefrontal Cortex is associated with impaired reversal learning in Sapap3-KOs, providing a likely neural basis for this observed heterogeneity. 30587851
2019-08-31 12:37:00 SAPAP3 mutation in the mouse model of obsessive-compulsive disorder impairs Pavlovian reversal learning. 30688005
2018-06-23 11:04:00 Recorded ultrasonic vocalizations (USVs) from 5-day-old sapap3 and sapap3 mice, and also monitored developmental reflexes in these mice during the early postnatal period. Sapap3 mice display an increase in the number and duration of USV calls relative to sapap3 littermates, despite otherwise similar developmental profiles. 29035974
2013-09-07 11:56:00 Both constitutive and induced genetic deletion of the melanocortin 4 receptor gene(MC4R) normalizes compulsive grooming and striatal electrophysiologic impairments in SAPAP3-null mice 23754400

名称对应

Type IDs
Synonymous BC058433, DAP-3, DAP3, Prpl8, Sapap3
Gene
UniProtKB-ID: DLGP3_MOUSE, B1AS06_MOUSE, Q3TY61_MOUSE
UniprotKB: Q6PFD5, B1AS06, Q3TY61
UniParc: UPI00004CBB09, UPI00001CDF45
EMBL: AL606984, AY243848, BC057615, BC058433, AK158868
Ensembl: ENSMUSG00000042388
KO: mmu:242667
Nucleutide sequences
EMBL-CDS: AAH58433.1, AAO89219.2, AAH57615.1, BAE34702.1
Ensembl_TRS: ENSMUST00000046659, ENSMUST00000106094, ENSMUST00000106092
Protein sequencees
Ensembl_PRO: ENSMUSP00000039724, ENSMUSP00000101700, ENSMUSP00000101698
RefSeq: XP_030109431.1, XP_030109432.1, XP_036020023.1, XP_006503168.1, XP_011238839.1, NP_941020.1, NP_001289010.1, XP_030109433.1, XP_006503167.1
Others
UniRef100: UniRef100_B1AS06, UniRef100_Q6PFD5
UniRef90: UniRef90_P97838
UniRef50: UniRef50_P97838
UniGene: Mm.331885
CCDS: CCDS18665.1

全选

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