Chgb - chromogranin B-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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24259 Chgb

基因描述

Type	Description
Definition	chromogranin B

研究结论

Date	Results	Publications
2020-07-18 12:12:00	CgB is necessary for efficient trafficking of secretory proteins into the budding granule, which impacts the availability of insulin-containing secretory granules for exocytic release.	31182646
2015-10-17 11:36:00	Possible involvement of Stat3 and Prlh1/Chgb up-regulation in the transition from short to repeated stress activation.	25217033
2014-05-17 15:04:00	When released extra-cellulary, CHGB proteolytic fragments exert a feedback effect to inhibit catecholamine secretion.	24266713
2011-12-08 17:54:00	Chrombacin is a 60 residue anti-microbial neuroendocrine peptide that includes an unusual sulfotyrosine-, phosphoserine-containing motif.	18181560
2010-01-21 00:00:00	CGB was localized in the nucleus; transcription control role of CGB in the nucleus	11854265

名称对应

Type	IDs
Gene	UniProtKB-ID: SCG1_RAT UniprotKB: O35314 UniParc: UPI00002510F4 EMBL: AF019974, BC128743 Ensembl: ENSRNOG00000021269 KO: rno:24259
Nucleutide sequences	EMBL-CDS: AAI28744.1, AAB72089.1 Ensembl_TRS: ENSRNOT00000028892
Protein sequencees	Ensembl_PRO: ENSRNOP00000028892 RefSeq: XP_006235134.1, NP_036658.2
Others	UniRef100: UniRef100_O35314 UniRef90: UniRef90_O35314 UniRef50: UniRef50_P23389 UniGene: Rn.11090

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
31182646	Chromogranin B regulates early-stage insulin granule trafficking from the Golgi in pancreatic islet Î²-cells. J. Cell. Sci. Shelby C Bearrows , Casey J Bauchle , McKenzie Becker , Jonathan M Haldeman , Svetha Swaminathan , Samuel B Stephens	2019-07-01	-
24266713	Chromogranin B: intra- and extra-cellular mechanisms to regulate catecholamine storage and release, in catecholaminergic cells and organisms. J. Neurochem. Kuixing Zhang , Nilima Biswas , Jiaur R Gayen , Jose Pablo Miramontes-Gonzalez , C Makena Hightower , Maja Mustapic , Manjula Mahata , Chun-Teng Huang , Vivian Y Hook , Sushil K Mahata , Sucheta Vaingankar , Daniel T O'Connor	2014-04-01	Chgb, Chgb
25217033	A systems approach identifies co-signaling molecules of early growth response 1 transcription factor in immobilization stress. BMC Syst Biol Nikolaos A Papanikolaou , Andrej Tillinger , Xiaoping Liu , Athanasios G Papavassiliou , Esther L Sabban	2014-01-01	Chgb, Stat3, Prlh
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
18437352	Beta cell chromogranin B is partially segregated in distinct granules and can be released separately from insulin in response to stimulation. Diabetologia T Giordano , C Brigatti , P Podini , E Bonifacio , J Meldolesi , M L Malosio	2008-06-01	-
18420944	Chromogranin B regulates calcium signaling, nuclear factor kappaB activity, and brain natriuretic peptide production in cardiomyocytes. Circ Res Felix M Heidrich , Kun Zhang , Manuel Estrada , Yan Huang , Frank J Giordano , Barbara E Ehrlich	2008-05-23	-
18181560	A sulfated, phosphorylated 7 kDa secreted peptide characterized by direct analysis of cell culture media. J. Proteome Res. Steven W Taylor , Chengzao Sun , Amy Hsieh , Nancy L Andon , Soumitra S Ghosh	2008-02-01	Chgb
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team	2004-10-01	Ldlrap1, Dnajc3, Rnaset2a, Btnl1, Isg15, Cyp3a41b, Ly6c2, Ccl21b, Eif3j2, Mup18, Lrrc19, Rcc1, 1700047I17Rik2, Pcsk9, Adat3, Tdrd7, Sco2, Gpr153, Pafah2, Gm44504, H6pd, Adprhl2, Gpn2, Rusc2, Stx12, Ppp1r8, Smpdl3b, Fam46b, Bsdc1, Slc44a1, Zfand2a, Rubcn, Kifc1, Pifo, C030017K20Rik, Cbarp, Rpl5, Micalcl, Atg14, Lrrc8c, Noc4l, Nsun5, Psph, Trrap, Mapre3, Ube3c, Tbc1d14, Hscb, Tyw1, Emilin1, Rab28, Pot1a, Parp11, Tada3, Tra2a, Brk1, Fbxl14, Phrf1, Plekha1, Gm21975, Ric8a, Mob2, Prkd2, Ccp110, Vrk3, Grwd1, Nlrp6, Trim68, Psip1, Spred3, Faap24, Ints4, Rrp8, Unc45a, Igflr1, Sf3b3, D8Ertd738e, Usb1, Champ1, Smim19, Exoc8, Gadd45gip1, Phkb, Dohh, Fam192a, Enkd1, Taf5l, Zdhhc7, Snapc2, Ak6, Gpat4, Dcun1d2, Ankrd10, Cog4, Hinfp, Lars2, Xylb, Imp3, Cmtm7
15060019	High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Genome Res. Anne E Kwitek , Jo Gullings-Handley , Jiaming Yu , Danilo C Carlos , Kimberly Orlebeke , Jeff Nie , Jeffrey Eckert , Angela Lemke , Jaime Wendt Andrae , Susan Bromberg , Dean Pasko , Dan Chen , Todd E Scheetz , Thomas L Casavant , M Bento Soares , Val C Sheffield , Peter J Tonellato , Howard J Jacob	2004-04-01	Hoxa1, Pitpnb, Txn1, Kcnj9, Phox2a, Cga, Gjb4, Kcnc3, Nr0b2, Mgst1, Sftpb, Unc50, Acadm, Acr, Adrb2, Afp, Akt1, Aldob, Akr1b1, Apeh, Atp1a3, Atp2b2, Atp4b, Atp7b, B2m, Tspo, C4bpa, C4bpb, Calca, Calm3, Cat, Cbs, Cd53, Psg19, Chga, Chgb, Ckm, Comt, Cryaa, Cryge, Prl3b1, Ctrb1, Cyp1a1, Cyp4b1, Dbp, Ddc, Egfr, Egr1, Eno1, Ets1, Fancc, Fbp1, Fuca1, Gad2, Gfap, Gfi1, Got1, Grin2b, Nr3c1, Hbb, Hrh1, Hspa1a, Htr1a, Iapp, Ibsp, Ifnb1, Igf1, Igfbp3, Il1b, Il5, Ins1, Irf1, Klk1, Lepr, Lpl, Mbl1, Me1, Mpg, Mt1, Muc1, Ncam1, Mme, Cgref1, Cxcl10, Nos1, Nppa, Npy, Oprd1, Orm1, S100a4, Pah, Serpine1, Pgm1, Pklr, Prl6a1, Pmch, Pomc, Prkca, Pthlh
12902350	Chromogranin B-induced secretory granule biogenesis: comparison with the similar role of chromogranin A. J Biol Chem Yang Hoon Huh , Soung Hoo Jeon , Seung Hyun Yoo	2003-10-17	-

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