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24258 Chga

24258

Chga

chromogranin A

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition chromogranin A

研究结论

Date Results Publications
2014-03-22 11:52:00 hypothesized that the 3'-UTR and promoter mutations lead to dysregulation (diminution) of Chga in brainstem cardiovascular control nuclei, ultimately contributing to the pathogenesis of hypertension in spontaneously hypertensive rats 23674521
2013-11-16 11:54:00 Data suggest that Chga plays role in cardiocirculatory homeostasis and allostasis in hypertension; in hypertension, negative inotropic effect elicited by full-length Chga in heart may represent compensatory mechanism for increased blood pressure. 23751870
2010-01-21 00:00:00 chromogranin A biosynthesis, proteolysis and the secretion of its derived peptides parallels that of the gonadotroph hormones throughout the oestrous cycle 12873792
2010-01-21 00:00:00 CgA is a master "on/off" switch regulating the formation of the dense-core secretory granule in neuroendocrine cells 12438143
2010-01-21 00:00:00 In mast cells, a chromogranin A-secretogranin III complex may play a key role in secretory granule biogenesis. 18802106

名称对应

Type IDs
Gene
UniProtKB-ID: Q5PPG5_RAT
UniprotKB: Q5PPG5
UniParc: UPI0000497A33
EMBL: BC087703, CH473982, AC108241
Ensembl: ENSRNOG00000052549
KO: rno:24258
Nucleutide sequences
EMBL-CDS: EDL81751.1, AAH87703.1
Gene_ORFName: rCG_21005
Ensembl_TRS: ENSRNOT00000090857
Protein sequencees
Ensembl_PRO: ENSRNOP00000070296
RefSeq: NP_067687.2
Others
UniRef100: UniRef100_Q5PPG5
UniRef90: UniRef90_P10354
UniRef50: UniRef50_P10354
UniGene: Rn.41024

全选

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研究热度

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