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242341 Atp6v0d2

242341

Atp6v0d2

ATPase, H+ transporting, lysosomal V0 subunit D2

protein-coding

Mus musculus

基因描述

Type Description
Definition ATPase, H+ transporting, lysosomal V0 subunit D2

研究结论

Date Results Publications
2021-02-20 13:29:00 Role of V-ATPase a3-Subunit in Mouse CTL Function. 32269094
2020-11-21 13:16:00 Innate immune responses through Toll-like receptor 3 require human-antigen-R-mediated Atp6v0d2 mRNA stabilization. 31892731
2020-06-20 11:42:00 Atp6v0d2-deficient macrophages have augmented mitochondrial damage, enhanced inflammasome activation and reduced clearance of Salmonella typhimurium. The susceptibility of atp6v0d2 knockout mice to DSS-induced colitis and Salmonella typhimurium-induced death, highlights the in vivo significance of ATP6V0D2-mediated autophagosome-lysosome fusion. 30681394
2020-05-16 10:44:00 The authors identified that ATP6V0d2 mediates leucine-induced mTORC1 activation in macrophages, which further regulates macrophage differentiation. 31134526
2019-12-21 10:47:00 Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2alpha-mediated tumor progression. 30431439

名称对应

Type IDs
Synonymous 1620401A02Rik, AI324824, V-ATPase
Gene
UniProtKB-ID: VA0D2_MOUSE
UniprotKB: Q80SY3
UniParc: UPI00000EA850
EMBL: AK170659, AK170578, AK089507, BC087899, AB088358, AY145896, AY517482, AK170405, AL773599, AL732527, AK075745, AK170072
Ensembl: ENSMUSG00000028238
KO: mmu:242341
Nucleutide sequences
EMBL-CDS: BAC57951.1, AAN61104.1, AAR99405.1, BAC40907.1, BAE41890.1, BAE41545.1, BAE41772.1, BAE41942.1, BAC35925.1, AAH87899.1
Ensembl_TRS: ENSMUST00000029900
Protein sequencees
Ensembl_PRO: ENSMUSP00000029900
RefSeq: XP_017175683.1, NP_780615.2
Others
UniRef100: UniRef100_Q80SY3
UniRef90: UniRef90_Q80SY3
UniRef50: UniRef50_Q8N8Y2
UniGene: Mm.19298
CCDS: CCDS17994.1

全选

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