| Type | Description |
|---|---|
| Definition | translocator protein |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 13:13:00 | TSPO expression is up-regulated under anoxia/reoxygenation injury, and repression of TSPO improves the endurance of cardiomyocytes. | 31707350 |
| 2019-03-16 10:55:00 | Study found no alcohol use disorder (AUD) group differences on [11C]PBR28 binding in our clinical study and no group differences in [11C]PBR28 uptake in the brain of alcohol-dependent versus -nondependent rats. However, when separately analyzing by TSPO genotype, found lower [11C]PBR28 binding in the brain of AUD patients than in healthy controls for medium-affinity binders only. | 29777199 |
| 2018-08-11 11:48:00 | These results suggest that the imidazole[1,2-a]pyridine-based radiotracer [(18)F]2 is a sensitive tool for noninvasively diagnosing myocarditis related to inflammation of the heart muscle by assessing abnormal TSPO expression. | 29342117 |
| 2018-05-26 11:16:00 | Data suggest that protein (18kDa) (TSPO) may represent a novel therapeutic target for depression in type 2 diabetes mellitus (T2DM). | 27886206 |
| 2017-12-02 11:16:00 | TSPO mutations in rats and a human polymorphism impair the rate of steroid synthesis. | 29074640 |
| Type | IDs |
|---|---|
| Synonymous | Bzrp, MBR, PTBZR02, Ptbzr, RATPTBZR02 |
| Gene |
UniProtKB-ID:
TSPO_RAT
UniprotKB:
P16257
UniParc:
UPI0000131B65
EMBL:
J05122,
M84221
Ensembl:
ENSRNOG00000010549
KO:
rno:24230
|
| Nucleutide sequences |
EMBL-CDS:
AAA41978.1,
AAA41862.1
Ensembl_TRS:
ENSRNOT00000014089
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000014089
RefSeq:
NP_036647.1
|
| Others |
UniRef100:
UniRef100_P16257
UniRef90:
UniRef90_P16257
UniRef50:
UniRef50_P30536
UniGene:
Rn.1820,
Rn.229367
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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