| Type | Description |
|---|---|
| Definition | ATPase plasma membrane Ca2+ transporting 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-24 12:22:00 | Although modification of PMCAs composition could provide some protection against calcium overload, reduction of PMCA2 appeared to be more detrimental to the cells than deficiency of PMCA3. Under pathological conditions, including inflammatory CCL5 action and long-lasting Ca(2+) dyshomeostasis, insufficient cell protection may result in progressive degeneration and death of neurons. | 31032369 |
| 2017-06-24 12:20:00 | higher occupancy of Calm2 and Calm3 promoters by NFATc2 and increased expression of these genes in response to NFATc2 silencing were demonstrated in PMCA2 and PMCA3-reduced lines. | 28153703 |
| 2015-06-20 12:17:00 | The results with PMCA2- or PMCA3-downregulated lines provide an evidence of a novel role of PMCA isoforms in regulation of bioenergetic pathways. | 25276815 |
| 2015-03-07 11:01:00 | GlyT2 activity is pre-synaptically controlled by physical and functional association with plasma membrane PMCA2, PMCA3, and NCX1. | 25315779 |
| 2015-03-07 11:01:00 | Plasma membrane PMCA2 and PMCA3 regulate cellular pH homeostasis in differentiating adrenal chromaffin cell line in a manner dependent on cytosolic Ca2+ elevations. | 25014339 |
| Type | IDs |
|---|---|
| Synonymous | PMCA2 |
| Gene |
UniProtKB-ID:
AT2B2_RAT
UniprotKB:
P11506
UniParc:
UPI00001BDC75,
UPI0001C2FACD,
UPI000002A449,
UPI0001C2FACF,
UPI00001BDC77,
UPI0001C2FACE,
UPI000002A447,
UPI000002A446,
UPI000002A448,
UPI00001261F2,
UPI0001C2FAD0,
UPI000002A44C,
UPI000002A44D,
UPI00001BDC76
EMBL:
AH005430,
J03754
Ensembl:
ENSRNOG00000030269
KO:
rno:24215
|
| Nucleutide sequences |
EMBL-CDS:
AAB60703.1,
AAA74219.1
Ensembl_TRS:
ENSRNOT00000067931
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000060489
RefSeq:
NP_036640.1
|
| Others |
UniRef100:
UniRef100_P11506
UniRef90:
UniRef90_Q9R0K7
UniRef50:
UniRef50_Q9R0K7
UniGene:
Rn.90982
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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