| Type | Description |
|---|---|
| Definition | Fras1 related extracellular matrix protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2012-08-25 11:28:00 | Report Fras1 up-regulation/Frem down-regulation in nephrons from mice with polycystic kidney disease and Frem2 mutations. | 21993971 |
| 2012-08-25 10:45:00 | The QBRICK, together with Frem2, defines the ability of BMs to bind integrin 81 through modulating the BM assembly of nephronectin, thereby regulating the integrin 81-mediated signals transmitted from the ureteric buds to the metanephric mesenchyme. | 22613833 |
| 2010-01-21 00:00:00 | QBRICK/Frem1, Fras1, and Frem2 interactions at the basement membrane have roles in preventing Fraser syndrome-like defects | 16880404 |
| 2010-01-21 00:00:00 | Fras1 is not only essential as a component of a macromolecular complex for the extracellular stabilization of Frem2 but it is also required for its proper intracellular trafficking and export from embryonic epithelial cells. | 17596926 |
| 2010-01-21 00:00:00 | expression of Frem2 may dynamically alter the extracellular matrix to provide a substrate for cell migration and rearrangements during embryogenesis | 16087869 |
| Type | IDs |
|---|---|
| Synonymous | 6030440P17Rik, 8430406N05Rik, Gm409, b2b1562Clo, my, ne, nv1 |
| Gene |
UniProtKB-ID:
FREM2_MOUSE
UniprotKB:
Q6NVD0
UniParc:
UPI00001933F4,
UPI0000519045,
UPI00000E9DD5
EMBL:
BC068185,
AB160988,
AK082256,
BC046388,
AK031494,
AJ833643
Ensembl:
ENSMUSG00000037016
KO:
mmu:242022
|
| Nucleutide sequences |
EMBL-CDS:
BAC27425.1,
CAH55760.1,
AAH68185.1,
BAC38448.1,
BAD89016.1,
AAH46388.1
Ensembl_TRS:
ENSMUST00000091137
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000088670
RefSeq:
XP_006501524.1,
XP_006501525.1,
NP_766450.2
|
| Others |
UniRef100:
UniRef100_Q6NVD0
UniRef90:
UniRef90_Q6NVD0
UniRef50:
UniRef50_Q5SZK8
UniGene:
Mm.38378
CCDS:
CCDS17348.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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