| Type | Description |
|---|---|
| Definition | N(alpha)-acetyltransferase 80, NatH catalytic subunit |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:26:00 | N-terminal acetylation of actin by NAA80 is essential for structural integrity of the Golgi apparatus. | 32209306 |
| 2019-06-15 11:02:00 | findings reveal that NAT6 plays a critical role in the maturation of actins by carrying out the acetylation of their N-terminal acidic residue | 30028079 |
| 2018-08-18 12:02:00 | this study reveals the molecular and cellular basis of NAA80 Nt acetylation and provides a scaffold for development of inhibitors for the regulation of cytoskeletal properties. | 29581307 |
| 2018-08-18 12:02:00 | the results demonstrate NAA80's role as actin's NAT and reveal a crucial role for actin Nt-acetylation in the control of cytoskeleton structure and dynamics. | 29581253 |
| 2018-04-05 09:36:00 | NAA80/NatH is dedicated to the post-translational N-terminal acetylation of processed actins. The structure of NAA80 reveals features like a positively charged catalytic groove perfectly suited to bind the acidic actin N-terminus. A cellular factor restricting NAA80 to processed actins is NatB, which co-translationally acetylates all cellular Met-starting N-termini with acidic amino acids at the second position. | 29581307 |
| Type | IDs |
|---|---|
| Synonymous | FUS-2, FUS2, HsNAAA80, NAT6 |
| Gene |
UniProtKB-ID:
NAA80_HUMAN,
Q6IAP1_HUMAN
UniprotKB:
Q93015,
Q6IAP1
UniParc:
UPI00001BD92D,
UPI000012FDA4
EMBL:
BC004483,
AF040705,
AF040706,
U73167,
CH471055,
CR457113,
AK313803
Ensembl:
ENSG00000243477
KO:
hsa:24142
|
| Nucleutide sequences |
EMBL-CDS:
AAC70913.1,
AAH04483.2,
AAC70912.1,
AAC02732.1,
EAW65077.1,
EAW65078.1,
EAW65080.1,
EAW65082.1,
CAG33394.1,
BAG36539.1,
EAW65081.1
Gene_ORFName:
hCG_2039743
Ensembl_TRS:
ENST00000354862,
ENST00000443842,
ENST00000443094,
ENST00000417393
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000400559,
ENSP00000346927,
ENSP00000410610,
ENSP00000391893
RefSeq:
NP_001186945.1,
NP_036323.2,
NP_001186947.1
|
| Others |
UniRef100:
UniRef100_Q93015
UniRef90:
UniRef90_Q93015
UniRef50:
UniRef50_Q93015
UniGene:
Hs.129910,
Hs.736942
CCDS:
CCDS56258.1,
CCDS43095.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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