| Type | Description |
|---|---|
| Definition | integrin alpha 8 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-01 11:31:00 | Role of integrin alpha8 in murine model of lung fibrosis | 29813125 |
| 2018-06-23 10:45:00 | Itga8-/- renal mesangial cells showed reduced phagocytosis of matrix-coated beads and apoptotic cells compared to WT renal mesangial cells. | 29544224 |
| 2018-05-26 12:09:00 | alpha8 Integrin is expressed in functional placental compartments among its ligands, OPN and/or FN, across species. Although this may point to a regulatory role in trophoblast function, our data from alpha8 integrin-deficient mice indicated only mild placental pathology. | 28136130 |
| 2018-05-05 10:08:00 | Study observed that in the Apoe-deficient model of atherosclerosis, the female sex is a risk factor to develop more severe atherosclerotic lesions, although serum fat levels are not higher in females than in males. In contrast, female mice are protected from renal damage induced by the concomitant deficiency of Apoe and Itga8 | 28572914 |
| 2017-12-02 11:39:00 | Mechanistically, ligation of alpha8beta1 by the milk protein Mfge8 reduces antral smooth muscle contractile force by preventing RhoA activation through a PTEN-dependent mechanism. | 27092791 |
| Type | IDs |
|---|---|
| Synonymous | AI447669 |
| Gene |
UniProtKB-ID:
ITA8_MOUSE
UniprotKB:
A2ARA8
UniParc:
UPI00001C257D,
UPI00000EAE11
EMBL:
AK044910,
AL845313,
AF041409,
AK031326,
AK135193
Ensembl:
ENSMUSG00000026768
KO:
mmu:241226
|
| Nucleutide sequences |
EMBL-CDS:
BAC27348.1,
BAE22455.1,
BAC32137.1,
AAC15665.1
Ensembl_TRS:
ENSMUST00000028106
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028106
RefSeq:
XP_006497539.1,
XP_006497538.1,
NP_001001309.1
|
| Others |
UniRef100:
UniRef100_A2ARA8
UniRef90:
UniRef90_A2ARA8
UniRef50:
UniRef50_P53708
UniGene:
Mm.329997
CCDS:
CCDS15689.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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