| Type | Description |
|---|---|
| Definition | sialidase 4 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-13 10:43:00 | Absence of Neu3 and Neu4 leads to defects in cell adhesion and differentiation of epithelial cells resulting in aberrant tubular offshoots that fail to remain connected with the main duct and male infertility. Hence Neu3 and Neu 4 play an essential role in the guidance of epithelial cells during early embryonic formation. | 30359429 |
| 2017-10-14 12:02:00 | These results provide the first in vivo evidence that neuraminidases 3 and 4 have important roles in CNS function by catabolizing gangliosides and preventing their storage in lipofuscin bodies. | 28442549 |
| 2012-07-07 11:57:00 | NEU4 is involved in regulation of neuronal function by polySia degradation in mammals. | 22393058 |
| 2011-01-08 10:56:00 | Neu4 is not the only sialidase contributing to the metabolic bypass in Hexa(-/-) mice. | 20862357 |
| 2010-01-21 00:00:00 | Neu4 is a functional component of the ganglioside-metabolizing system, contributing to the postnatal development of the brain and other vital organs. | 18270209 |
| Type | IDs |
|---|---|
| Synonymous | 9330166I04 |
| Gene |
UniProtKB-ID:
NEUR4_MOUSE,
C5NTX9_MOUSE
UniprotKB:
Q8BZL1,
C5NTX9
UniParc:
UPI00000EA3F0,
UPI0000223B82
EMBL:
AK034236,
AB510404,
AY258421,
BC070438
Ensembl:
ENSMUSG00000034000
KO:
mmu:241159
|
| Nucleutide sequences |
EMBL-CDS:
BAC28641.1,
AAH70438.1,
AAP81169.1,
BAH79965.1
Ensembl_TRS:
ENSMUST00000050890,
ENSMUST00000190212
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000140127,
ENSMUSP00000051151
RefSeq:
NP_001297698.1,
NP_776133.1
|
| Others |
UniRef100:
UniRef100_Q8BZL1
UniRef90:
UniRef90_Q8BZL1
UniRef50:
UniRef50_Q8WWR8
UniGene:
Mm.214565
CCDS:
CCDS15199.1,
CCDS78660.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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