| Type | Description |
|---|---|
| Definition | bestrophin 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 12:22:00 | NEDD4L is an E3 ubiquitin ligase of bestrophin-1. WW3-4 domains of NEDD4L are required for the interaction with bestrophin-1.Lysine370 of BEST1 plays a critical role in poly-ubiquitination. | 31036321 |
| 2018-07-28 10:47:00 | 14-3-3gamma promotes surface expression of Best1 channel in astrocytes through direct interaction. | 29121962 |
| 2016-04-23 11:24:00 | Data suggest that the ion channels CaV1.3, bestrophin-1 and maxiK were identified as players in the regulation of photoreceptor outer segments (POS) phagocytosis by the retinal pigment epithelium (RPE). | 26427483 |
| 2015-11-28 10:38:00 | Best1-mediated astrocytic glutamate activates the synaptic N-methyl-D-aspartate receptor (NMDAR) and modulates NMDAR-dependent synaptic plasticity. | 25645137 |
| 2014-07-26 12:44:00 | Bestrophin-1 functions as an intracellular Cl channel which helps to accumulate and to release Ca(2+) from stores by conducting the counterion for Ca(2+). | 24664688 |
| Type | IDs |
|---|---|
| Synonymous | Bmd, Vmd2, mBest1 |
| Gene |
UniProtKB-ID:
BEST1_MOUSE
UniprotKB:
O88870
UniParc:
UPI000015E3DB
EMBL:
AF057171,
BC139061,
BC139060,
AY450427
Ensembl:
ENSMUSG00000037418
KO:
mmu:24115
|
| Nucleutide sequences |
EMBL-CDS:
AAI39062.1,
AAC64345.1,
AAS09922.1,
AAI39061.1
Ensembl_TRS:
ENSMUST00000117346
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000113053
RefSeq:
NP_036043.2
|
| Others |
UniRef100:
UniRef100_O88870
UniRef90:
UniRef90_O88870
UniRef50:
UniRef50_O88870
UniGene:
Mm.31577
CCDS:
CCDS29568.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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