例如:"NBL1", "4681", "drought"
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24115 Best1

24115

Best1

bestrophin 1

protein-coding

Mus musculus

基因描述

Type Description
Definition bestrophin 1

研究结论

Date Results Publications
2020-07-25 12:22:00 NEDD4L is an E3 ubiquitin ligase of bestrophin-1. WW3-4 domains of NEDD4L are required for the interaction with bestrophin-1.Lysine370 of BEST1 plays a critical role in poly-ubiquitination. 31036321
2018-07-28 10:47:00 14-3-3gamma promotes surface expression of Best1 channel in astrocytes through direct interaction. 29121962
2016-04-23 11:24:00 Data suggest that the ion channels CaV1.3, bestrophin-1 and maxiK were identified as players in the regulation of photoreceptor outer segments (POS) phagocytosis by the retinal pigment epithelium (RPE). 26427483
2015-11-28 10:38:00 Best1-mediated astrocytic glutamate activates the synaptic N-methyl-D-aspartate receptor (NMDAR) and modulates NMDAR-dependent synaptic plasticity. 25645137
2014-07-26 12:44:00 Bestrophin-1 functions as an intracellular Cl channel which helps to accumulate and to release Ca(2+) from stores by conducting the counterion for Ca(2+). 24664688

名称对应

Type IDs
Synonymous Bmd, Vmd2, mBest1
Gene
UniProtKB-ID: BEST1_MOUSE
UniprotKB: O88870
UniParc: UPI000015E3DB
EMBL: AF057171, BC139061, BC139060, AY450427
Ensembl: ENSMUSG00000037418
KO: mmu:24115
Nucleutide sequences
EMBL-CDS: AAI39062.1, AAC64345.1, AAS09922.1, AAI39061.1
Ensembl_TRS: ENSMUST00000117346
Protein sequencees
Ensembl_PRO: ENSMUSP00000113053
RefSeq: NP_036043.2
Others
UniRef100: UniRef100_O88870
UniRef90: UniRef90_O88870
UniRef50: UniRef50_O88870
UniGene: Mm.31577
CCDS: CCDS29568.1

全选

研究热度
发表文献
研究结论
热点单位
排名 科研单位 文献
1

Korea Institute of Science and Technology (KIST)

7
2

Korea Institute of Science and Technology

5
3

Kyungpook National University

3
4

Institut für Physiologie

3
5

Kyung Hee University

2
热点人员
排名 研究人员 文献
1

C Justin Lee

12
2

Soo-Jin Oh

8
3

P Carninci

7
4

Bo-Eun Yoon

7
5

Kyung-Seok Han

7
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