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24110 Usp18

24110

Usp18

ubiquitin specific peptidase 18

protein-coding

Mus musculus

基因描述

Type Description
Definition ubiquitin specific peptidase 18

研究结论

Date Results Publications
2020-09-26 13:05:00 USP18 Overexpression Protects against Focal Cerebral Ischemia Injury in Mice by Suppressing Microglial Activation. 31513843
2019-09-14 10:12:00 Deletion of Usp18 in mouse dendritic cells was sufficient to enhance host control of infections with two strains of Gram-positive bacteria. Normal induction of USP18 after infection impaired antibacterial responses mediated by tumor necrosis factor. These findings spotlight USP18 as a new potential target for therapeutics aimed at improving control of serious bacterial infections. 30266866
2018-04-14 11:20:00 Usp18 protects the cells from oxidative stress-induced apoptosis which may be through the regulation of p53 and caspase 3. 28557172
2017-12-02 10:55:00 associates with and deubiquitinates TAK1 to protect against hepatic steatosis, insulin resistance, and the inflammatory response 28718215
2017-08-12 11:14:00 this study identifies the osteopenia phenotype of mice lacking Usp18, which is known as a negative regulator of type I IFN signaling 27016605

名称对应

Type IDs
Synonymous 1110058H21Rik, AW047653, UBP43, Ubp15
Gene
UniProtKB-ID: UBP18_MOUSE, Q3UAR6_MOUSE
UniprotKB: Q9WTV6, Q3UAR6
UniParc: UPI00005ACA80, UPI0000563B9D
EMBL: AF069502, AK152034, AK152574, AK151260, AK153312, AK151011, AK151722
Ensembl: ENSMUSG00000030107
KO: mmu:24110
Nucleutide sequences
EMBL-CDS: BAE31326.1, AAD21222.1, BAE31893.1, BAE30893.1, BAE30248.1, BAE30640.1, BAE30032.1
Ensembl_TRS: ENSMUST00000032198
Protein sequencees
Ensembl_PRO: ENSMUSP00000032198
RefSeq: NP_036039.2
Others
UniRef100: UniRef100_Q9WTV6, UniRef100_Q3UAR6
UniRef90: UniRef90_Q9WTV6
UniRef50: UniRef50_Q9UMW8
UniGene: Mm.326911
CCDS: CCDS20489.1

全选

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研究热度

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