| Type | Description |
|---|---|
| Definition | RanBP-type and C3HC4-type zinc finger containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 10:49:00 | catalyses ester bond formation between ubiquitin and components of the Myddosome, indicating a role in regulating innate immunity | 31209050 |
| 2019-10-05 10:22:00 | LUBAC-tethering motifs (LTMs) located N terminally to the UBL domains of HOIL-1L and heterodimerize and fold into a single globular domain. | 29694895 |
| 2019-01-19 10:50:00 | Data show that keratinocyte-specific deletion of ubiquitin-protein ligases HOIP, HOIL-1 (E-KO) and shank-interacting protein-like 1 protein results in severe dermatitis causing postnatal lethality. | 30254289 |
| 2018-09-29 12:15:00 | results demonstrate that both HOIP and HOIL-1 are essential LUBAC components and are required for embryogenesis by preventing aberrant cell death; furthermore, they reveal that when LUBAC and caspase-8 are absent, RIPK3 prevents RIPK1 from inducing embryonic lethality by causing defects in fetal haematopoiesis | 29695863 |
| 2018-07-07 10:57:00 | HIF regulation of HOIL-1L targets the phosphorylated for degradation and serves as an hypoxia-adaptive mechanism to stabilize the Na,K-ATPase, avoiding significant lung injury. | 29109255 |
| Type | IDs |
|---|---|
| Synonymous | AL033326, HOIL-1, HOIL-1L, UIP28, Ubce7ip3 |
| Gene |
UniProtKB-ID:
HOIL1_MOUSE
UniprotKB:
Q9WUB0
UniParc:
UPI00001EE2A2
EMBL:
AL831735,
AK088591,
BC034555,
AK166075,
AF124663,
AL928568
Ensembl:
ENSMUSG00000027466
KO:
mmu:24105
|
| Nucleutide sequences |
EMBL-CDS:
BAC40440.1,
AAD24572.1,
BAE38556.1,
AAH34555.1
Ensembl_TRS:
ENSMUST00000028964,
ENSMUST00000109847
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028964,
ENSMUSP00000105473
RefSeq:
XP_006499510.1,
NP_001342211.1,
XP_030106804.1,
NP_062679.2,
XP_006499509.1,
XP_030106806.1,
XP_006499508.1,
XP_030106805.1,
NP_001077390.1
|
| Others |
UniRef100:
UniRef100_Q9WUB0
UniRef90:
UniRef90_Q62921
UniRef50:
UniRef50_Q62921
UniGene:
Mm.182145
CCDS:
CCDS38273.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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