| Type | Description |
|---|---|
| Definition | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:31:00 | Exuberant fibroblast activity compromises lung function via ADAMTS4. | 33116313 |
| 2020-03-28 10:52:00 | ADAMTS4 was exclusively expressed in oligodendrocytes | 30426203 |
| 2019-07-06 10:30:00 | Aortas in Adamts-4-/- mice showed reduced elastic fiber destruction, versican degradation, macrophage infiltration, and apoptosis. Interestingly, Adamts-4 was directly involved in smooth muscle cell (SMC) apoptosis. Study findings indicate that Adamts-4 induces SMC apoptosis, degrades versican, promotes inflammatory cell infiltration, and thus contributes to sporadic aortic aneurysm and dissection development. | 28955046 |
| 2018-11-10 11:58:00 | host-derived ADAMTS4 was expressed at the tumor vessels and was associated with early-stage tumor growth. | 29926003 |
| 2018-06-09 10:56:00 | This study demonstrated that ADAMTS-4 is a new marker of mature oligodendrocytes contributing to the myelination processes and thus to the control of motor capacities. | 28850711 |
| Type | IDs |
|---|---|
| Synonymous | ADAM-TS4, ADAMTS-2, ADMP-1 |
| Gene |
UniProtKB-ID:
ATS4_MOUSE
UniprotKB:
Q8BNJ2
UniParc:
UPI00001EDECE
EMBL:
BC027773,
AK083534
Ensembl:
ENSMUSG00000006403
KO:
mmu:240913
|
| Nucleutide sequences |
EMBL-CDS:
AAH27773.1,
BAC38944.1
Ensembl_TRS:
ENSMUST00000111315
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000106947
RefSeq:
NP_766433.2
|
| Others |
UniRef100:
UniRef100_Q8BNJ2
UniRef90:
UniRef90_Q8BNJ2
UniRef50:
UniRef50_O75173
UniGene:
Mm.491147
CCDS:
CCDS15485.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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