| Type | Description |
|---|---|
| Definition | phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:29:00 | Class II phosphatidylinositol 3-kinase alpha and beta isoforms are required for vascular smooth muscle Rho activation, contraction and blood pressure regulation in mice. | 32192434 |
| 2020-02-01 13:08:00 | Both PI3K-C2alpha and PI3K-C2beta are required for normal uterine smooth muscle contraction and parturition mainly through their involvement in Rhoa activation. | 30476019 |
| 2017-09-30 11:13:00 | Pik3c2b is a genetic modifier of Mtm1 mutation with a role in function and survival in myotubular myopathy animal models | 27548528 |
| 2016-06-28 11:47:00 | Modulation of and PI3KC2beta activity to control of KCa3.1 channel expression can be an alternative important target to attenuate ascending thoracic aortic aneurysms in Fabry disease. | 26820527 |
| 2012-10-13 10:14:00 | study found that TRIM27 negatively regulates FcepsilonRI activation of KCa3.1 and downstream signaling by ubiquitinating and inhibiting PI3KC2beta | 22645315 |
| Type | IDs |
|---|---|
| Synonymous | C330011J12Rik, Gm199, PI3K-C2beta, PI3KC2beta |
| Gene |
UniProtKB-ID:
E9QAN8_MOUSE
UniprotKB:
E9QAN8
UniParc:
UPI0000434698
EMBL:
AC137948,
AC107842
Ensembl:
ENSMUSG00000026447
KO:
mmu:240752
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000077730
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000076911
RefSeq:
XP_006529594.1,
XP_006529595.1,
NP_001092746.2,
XP_006529596.1
|
| Others |
UniRef100:
UniRef100_E9QAN8
UniRef90:
UniRef90_E9QAN8
UniRef50:
UniRef50_O00750
UniGene:
Mm.387308
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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