| Type | Description |
|---|---|
| Definition | sprouty RTK signaling antagonist 4 |
| Date | Results | Publications |
|---|---|---|
| 2018-08-11 12:01:00 | A Sprouty4 reporter to monitor FGF/ERK signaling activity in ESCs and mice. | 29964027 |
| 2017-10-07 12:02:00 | Irf6 and RTK signaling interact in regulating periderm differentiation and function, as well as provide a rationale to screen for epistatic interactions between variants in IRF6 and RTK signaling pathway genes in human orofacial clefting populations. | 28732181 |
| 2017-01-14 11:35:00 | In the present study, it is demonstrated that Spry2 and -4 participate in KA induced neurodegeneration possibly through inhibition of ERK signaling. | 26540287 |
| 2016-04-16 10:45:00 | Autoregulatory loop between TGF-beta1/miR-411-5p/SPRY4 and p38 MAPK pathway in rhabdomyosarcoma modulates proliferation and differentiation. | 26291313 |
| 2016-01-30 10:45:00 | in embryos with lower Spry2;Spry4 gene dosages, we observed a non-fusion of original R2 and M1 Shh signaling domains with consequent formation of a supernumerary tooth primordium from the isolated R2 bud | 25897685 |
| Type | IDs |
|---|---|
| Synonymous | A030006O18Rik, sprouty4 |
| Gene |
UniProtKB-ID:
SPY4_MOUSE
UniprotKB:
Q9WTP2
UniParc:
UPI0000004000
EMBL:
AK037180,
AB019280,
AK048122,
BC057005,
AF176906,
BC050944,
CH466528
Ensembl:
ENSMUSG00000024427
KO:
mmu:24066
|
| Nucleutide sequences |
EMBL-CDS:
AAH50944.1,
BAC33249.1,
BAC29739.1,
BAA77689.1,
AAD56007.1,
AAH57005.1,
EDL10072.1
Ensembl_TRS:
ENSMUST00000025295
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000025295
RefSeq:
NP_036028.2,
XP_036017041.1
|
| Others |
UniRef100:
UniRef100_Q9WTP2
UniRef90:
UniRef90_Q9WTP2
UniRef50:
UniRef50_Q9WTP2
UniGene:
Mm.42038
CCDS:
CCDS29202.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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