| Type | Description |
|---|---|
| Definition | potassium channel, subfamily V, member 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-25 11:00:00 | Kv8.2 knock-out (KO) mice show many similarities to human cone dystrophy with a supernormal rod response, including a depressed a-wave and an elevated b-wave response with bright light stimulation. Optical coherence tomography imaging and immunohistochemistry indicate that the changes in six-month-old Kv8.2 KO retinae are largely limited to the outer nuclear layer, while outer segments appear intact. | 30820446 |
| 2014-07-26 12:44:00 | We conclude that nucleotide changes in evolutionary conserved crx binding site could impact retina-specific expression levels of Kcnv2. | 24664678 |
| 2013-03-02 13:12:00 | two pore mutations (W467G and G478R) led to the formation of nonconducting heteromeric Kv2.1/Kv8.2 channels | 23115240 |
| 2011-06-18 11:33:00 | Results demonstrate that altered potassium subunit function influences epilepsy susceptibility and implicate Kcnv2 as an epilepsy gene. | 21402906 |
| 2010-01-21 00:00:00 | Kcnv2 is a strong functional candidate for epilepsy modifier. | 19513789 |
| Type | IDs |
|---|---|
| Synonymous | KV11.1 |
| Gene |
UniProtKB-ID:
KCNV2_MOUSE
UniprotKB:
Q8CFS6
UniParc:
UPI00000E8F84
EMBL:
BC039042,
AY238939
Ensembl:
ENSMUSG00000047298
KO:
mmu:240595
|
| Nucleutide sequences |
EMBL-CDS:
AAH39042.1,
AAP70480.1
Ensembl_TRS:
ENSMUST00000056708
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000055091
RefSeq:
NP_899002.1,
XP_006527130.1
|
| Others |
UniRef100:
UniRef100_Q8CFS6
UniRef90:
UniRef90_Q8CFS6
UniRef50:
UniRef50_Q8TDN2
UniGene:
Mm.269759
CCDS:
CCDS29722.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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