例如:"NBL1", "4681", "drought"
收藏
24053 Sgcg

24053

Sgcg

sarcoglycan, gamma (dystrophin-associated glycoprotein)

protein-coding

Mus musculus

基因描述

Type Description
Definition sarcoglycan, gamma (dystrophin-associated glycoprotein)

研究结论

Date Results Publications
2017-09-30 12:14:00 Cleavage of beta-DG still occurred when both MMP-2 and MMP-9 were knocked out in gamma - sarcoglycan-deficient mice. The study found that up-regulation of MMP-14 is capable of cleaving beta-DG, and it may be involved in the pathogenesis of sarcoglycanopathy. 28821434
2016-03-12 11:07:00 for MD research. The Sgcg(-/-) mice have a more severe phenotype than the mdx mice. Muscle function was assessed by plethysmography and echocardiography. Histologically the Sgcg(-/-) mice displayed increased fibrosis and variable fiber size. 26064876
2015-12-26 11:47:00 These results position archvillin as a mechanically sensitive component of the dystrophin complex and demonstrate that signaling defects caused by loss of gamma-SG occur both at the sarcolemma and in the nucleus. 25605665
2011-11-12 12:17:00 This study supports a model where dystrophin, but not the sarcoglycans, protects the cardiac myocyte against mechanical damage. 21665956
2010-06-28 11:07:00 localization of gamma-SG does not require Tyr(6), but localization alone is insufficient for restoration of normal signal transduction patterns after mechanical perturbation 20371873

名称对应

Type IDs
Synonymous 35kDa, 5430420E18Rik, AI642964, gamma-SG
Gene
UniProtKB-ID: SGCG_MOUSE, Q9EQ83_MOUSE
UniprotKB: P82348, Q9EQ83
UniParc: UPI0000024D30
EMBL: AB024922, AK132610, BC138960, BC138961, AF282901
Ensembl: ENSMUSG00000035296
KO: mmu:24053
Nucleutide sequences
EMBL-CDS: BAA83493.1, AAI38961.1, BAE21260.1, AAI38962.1, AAG16770.1
Ensembl_TRS: ENSMUST00000077954, ENSMUST00000121148
Protein sequencees
Ensembl_PRO: ENSMUSP00000077106, ENSMUSP00000112576
RefSeq: XP_036014490.1, NP_036022.1
Others
UniRef100: UniRef100_P82348
UniRef90: UniRef90_P82348
UniRef50: UniRef50_P82347
UniGene: Mm.72173
CCDS: CCDS27181.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员