Type | Description |
---|---|
Definition | sarcoglycan, gamma (dystrophin-associated glycoprotein) |
Date | Results | Publications |
---|---|---|
2017-09-30 12:14:00 | Cleavage of beta-DG still occurred when both MMP-2 and MMP-9 were knocked out in gamma - sarcoglycan-deficient mice. The study found that up-regulation of MMP-14 is capable of cleaving beta-DG, and it may be involved in the pathogenesis of sarcoglycanopathy. | 28821434 |
2016-03-12 11:07:00 | for MD research. The Sgcg(-/-) mice have a more severe phenotype than the mdx mice. Muscle function was assessed by plethysmography and echocardiography. Histologically the Sgcg(-/-) mice displayed increased fibrosis and variable fiber size. | 26064876 |
2015-12-26 11:47:00 | These results position archvillin as a mechanically sensitive component of the dystrophin complex and demonstrate that signaling defects caused by loss of gamma-SG occur both at the sarcolemma and in the nucleus. | 25605665 |
2011-11-12 12:17:00 | This study supports a model where dystrophin, but not the sarcoglycans, protects the cardiac myocyte against mechanical damage. | 21665956 |
2010-06-28 11:07:00 | localization of gamma-SG does not require Tyr(6), but localization alone is insufficient for restoration of normal signal transduction patterns after mechanical perturbation | 20371873 |
Type | IDs |
---|---|
Synonymous | 35kDa, 5430420E18Rik, AI642964, gamma-SG |
Gene |
UniProtKB-ID:
SGCG_MOUSE,
Q9EQ83_MOUSE
UniprotKB:
P82348,
Q9EQ83
UniParc:
UPI0000024D30
EMBL:
AB024922,
AK132610,
BC138960,
BC138961,
AF282901
Ensembl:
ENSMUSG00000035296
KO:
mmu:24053
|
Nucleutide sequences |
EMBL-CDS:
BAA83493.1,
AAI38961.1,
BAE21260.1,
AAI38962.1,
AAG16770.1
Ensembl_TRS:
ENSMUST00000077954,
ENSMUST00000121148
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000077106,
ENSMUSP00000112576
RefSeq:
XP_036014490.1,
NP_036022.1
|
Others |
UniRef100:
UniRef100_P82348
UniRef90:
UniRef90_P82348
UniRef50:
UniRef50_P82347
UniGene:
Mm.72173
CCDS:
CCDS27181.1
|
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