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24051 Sgcb

24051

Sgcb

sarcoglycan, beta (dystrophin-associated glycoprotein)

protein-coding

Mus musculus

基因描述

Type Description
Definition sarcoglycan, beta (dystrophin-associated glycoprotein)

研究结论

Date Results Publications
2018-03-03 11:47:00 Generate a new knock-in model carrying the missense mutation T151R in the beta-sarcoglycan gene since this is the second sarcoglycan protein with the most frequently reported missense mutations. Muscle analysis, performed at the age of 4 and 9-months, showed the presence of the mutated beta-sarcoglycan protein and of the other components of the dystrophin-associated glycoprotein complex at the muscle membrane. 29360879
2017-09-09 10:47:00 beta-Sarcoglycan deficiency reduces atherosclerotic plaque formation in ApoE-knockout mouse model. 28768281
2015-01-17 12:34:00 In Sgcb-null mice, severe morphological disruption was present from 4 weeks in both quadriceps and diaphragm, and included conspicuous deposition of extracellular matrix components. 24723230
2012-01-14 10:45:00 Aging leads to changes in expression of beta-sarcoglycan in aged affected muscles (diaphragm and limb). 22102469
2010-01-21 00:00:00 Sarcoglycan beta missense mutations affect sarcoglycan complex assembly and/or localization to the cell surface and provide information on the molecular mechanisms underlying the effects of various sarcoglycan mutations in muscular dystrophies. 16524571

名称对应

Type IDs
Synonymous 43DAG, AI747103, AI844814, beta-SG
Gene
UniProtKB-ID: SGCB_MOUSE
UniprotKB: P82349
UniParc: UPI0000028E87
EMBL: AF169288, AK014381, AB024921, BC052349, AK132306, AK169403
Ensembl: ENSMUSG00000029156
KO: mmu:24051
Nucleutide sequences
EMBL-CDS: BAA83492.1, AAF28458.1, BAB29310.1, AAH52349.1, BAE21093.1, BAE41149.1
Ensembl_TRS: ENSMUST00000081170
Protein sequencees
Ensembl_PRO: ENSMUSP00000079937
RefSeq: NP_036020.1
Others
UniRef100: UniRef100_P82349
UniRef90: UniRef90_P82349
UniRef50: UniRef50_Q16585
UniGene: Mm.89310
CCDS: CCDS19344.1

全选

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