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24047 Ccl19

24047

Ccl19

chemokine (C-C motif) ligand 19

protein-coding

Mus musculus

基因描述

Type Description
Definition chemokine (C-C motif) ligand 19

研究结论

Date Results Publications
2020-05-23 12:43:00 Astrocyte-derived CCL19 was required for age-related gliosis-induced central nervous system lymphoma (CNSL). Deleting CCL19 in mice or CCR7 from lymphoma cells (LCs) abrogated CNSL development. Aged, gliotic wild-type mice were more susceptible to forming CNSL than young wild-type mice, and astrocytic CCL19 was observed in both human gliosis and CNSL. 31526758
2019-09-21 10:54:00 CCL19-expressing fibroblastic stromal cells in murine lung carcinoma control tumor growth 29391257
2019-04-22 10:25:00 Graft Site Microenvironment Determines Dendritic Cell Trafficking Through the CCR7-CCL19/21 Axis. 27031839
2018-12-22 12:11:00 We engineered CAR-T cells to express interleukin (IL)-7 and CCL19 (7 x 19 CAR-T cells), as these factors are essential for the maintenance of T-cell zones in lymphoid organs... Following treatment of mice with 7 x 19 CAR-T cells, both recipient conventional T cells and administered CAR-T cells generated memory responses against tumors. 29505028
2018-02-17 11:43:00 These data show that CCR7-CCL19/CCL21 axis facilitates retention CD4(+) T lymphocytes at the site of collateral artery remodeling, which is essential for effective arteriogenesis. 28275068

名称对应

Type IDs
Synonymous CKb11, ELC, MIP3B, Scya19, exodus-3
Gene
UniProtKB-ID: CCL19_MOUSE, Q548P0_MOUSE
UniprotKB: O70460, Q548P0
UniParc: UPI0000000942
EMBL: AF307988, BC051472, AK144337, AF308159, AF059208
Ensembl: ENSMUSG00000094661, ENSMUSG00000071005
KO: mmu:24047
Nucleutide sequences
EMBL-CDS: AAC14661.1, AAH51472.1, BAE25839.1, AAG45836.1, AAG30538.1
Ensembl_TRS: ENSMUST00000118540, ENSMUST00000102957
Protein sequencees
Ensembl_PRO: ENSMUSP00000137353, ENSMUSP00000100022
RefSeq: NP_036018.1
Others
UniRef100: UniRef100_O70460
UniRef90: UniRef90_O70460
UniRef50: UniRef50_O70460
UniGene: Mm.6660, Mm.426373, Mm.459263
CCDS: CCDS18080.1

全选

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