Type | Description |
---|---|
Definition | sodium channel, voltage-gated, type XI, alpha |
Date | Results | Publications |
---|---|---|
2020-10-10 13:03:00 | Gain-of-function mutation in SCN11A causes itch and affects neurogenic inflammation and muscle function in Scn11a+/L799P mice. | 32817686 |
2020-01-04 10:09:00 | abnormal activation of Nav1.9 channels by Nitric Oxide (NO) is responsible for MOH induced by triptan migraine medicine. Deletion of the Scn11a gene in Medication-overuse headache mice abrogates NO-mediated symptoms, including cephalic and extracephalic allodynia, photophobia and phonophobia. | 31534133 |
2019-11-02 10:24:00 | crucial for shaping the action potential upstroke and keeping the NaV1.8 voltage threshold within reach | 29970412 |
2019-09-21 11:27:00 | data suggest an important contribution of NaV1.9 to itch signaling. | 30395542 |
2019-05-04 11:40:00 | Two missense var- iants, p.R222S and p.R222H of Nav1.9, were identified in SCN11A by linkage analysis and exome analy- sis | 30549873 |
Type | IDs |
---|---|
Synonymous | NSS2, NaN, NaT, NaV1.9, SNS2 |
Gene |
UniProtKB-ID:
SCNBA_MOUSE
UniprotKB:
Q9R053
UniParc:
UPI00001F75CB
EMBL:
AC124662,
AB031389,
AF118044,
AC162937
Ensembl:
ENSMUSG00000034115
KO:
mmu:24046
|
Nucleutide sequences |
EMBL-CDS:
BAA92154.1,
AAD53403.1
Ensembl_TRS:
ENSMUST00000215718,
ENSMUST00000070617
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000149420,
ENSMUSP00000065466
RefSeq:
XP_017168851.1,
NP_036017.3
|
Others |
UniRef100:
UniRef100_Q9R053
UniRef90:
UniRef90_Q9R053
UniRef50:
UniRef50_Q9R053
UniGene:
Mm.89981
CCDS:
CCDS40804.1
|
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Refseq |
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