| Type | Description |
|---|---|
| Definition | SET binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 10:04:00 | myeloid transformation requires the interaction of XPO1 with SETBP1 | 31337858 |
| 2018-02-24 11:45:00 | Myb knockdown in Setbp1 and Setbp1 missense mutations-induced AML cells also efficiently induced their differentiation in culture and significantly prolonged the survival of their secondary recipient mice. | 27863435 |
| 2017-06-24 12:19:00 | We demonstrated that Nup98-TopIIbeta and Nup98-SETBP1 negatively regulate the XPO1-mediated protein export. Our results will contribute to the understanding of the molecular mechanism by which the Nup98-fusion proteins induce tumorigenesis. | 28392395 |
| 2016-06-04 11:31:00 | Setbp1 overexpression also causes transcriptional repression of critical hematopoiesis regulator gene Runx1 | 26205084 |
| 2012-09-15 10:30:00 | Setbp1 promotes the self-renewal of murine myeloid progenitors via activation of Hoxa9 and Hoxa10. | 22566606 |
| Type | IDs |
|---|---|
| Synonymous | C130092E12, Seb, mKIAA0437 |
| Gene |
UniProtKB-ID:
SETBP_MOUSE
UniprotKB:
Q9Z180
UniParc:
UPI00004296C7
EMBL:
AC140455,
AC131736,
BC080865,
AC114924,
AC146613,
AB015614,
AK129143
Ensembl:
ENSMUSG00000024548
KO:
mmu:240427
|
| Nucleutide sequences |
EMBL-CDS:
AAH80865.1,
BAA36338.1,
BAC97953.1
Ensembl_TRS:
ENSMUST00000025430
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000025430
RefSeq:
NP_444329.2
|
| Others |
UniRef100:
UniRef100_Q9Z180
UniRef90:
UniRef90_Q9Z180
UniRef50:
UniRef50_Q9Y6X0
UniGene:
Mm.312871
CCDS:
CCDS29362.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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