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240168 Rasgrp3

240168

Rasgrp3

RAS, guanyl releasing protein 3

protein-coding

Mus musculus

基因描述

Type Description
Definition RAS, guanyl releasing protein 3

研究结论

Date Results Publications
2019-06-22 12:06:00 RasGRP3 is specifically required for GNAQ/GNA11-driven Ras activation and tumorigenesis. 29490280
2017-08-05 10:43:00 RasGRP1/3-deficient progenitors show impaired migration toward the CCR9 ligand, CCL25, suggesting that RasGRP1 and RasGRP3 may regulate progenitor entry into the thymus through a CCR9-dependent mechanism. 27465532
2016-03-12 11:20:00 RasGRP3 limits inflammatory response by activating Rap1 on low-intensity pathogen infection, setting a threshold for preventing excessive inflammatory response. 25118589
2013-07-06 11:24:00 RasGRP1, but not RasGRP3, is required for thymocyte positive selection and invariant natural killer T cell selection. 23308188
2011-07-23 10:25:00 Expressed in developing blood vessels, Rasgrp3 contributes to the incidence of cardiovascular defects found in embryos from diabetic mothers. 21474816

名称对应

Type IDs
Synonymous BC066069, Gm327
Gene
UniProtKB-ID: Q6NZH9_MOUSE
UniprotKB: Q6NZH9
UniParc: UPI000023B75D
EMBL: CT010501, BC066127, AC118018, BC066069
Ensembl: ENSMUSG00000071042
KO: mmu:240168
Nucleutide sequences
EMBL-CDS: AAH66069.1, AAH66127.1
Ensembl_TRS: ENSMUST00000164192, ENSMUST00000095204
Protein sequencees
Ensembl_PRO: ENSMUSP00000092828, ENSMUSP00000129393
RefSeq: XP_006524334.1, XP_006524336.1, NP_001347032.1, NP_001159965.1, NP_997129.1
Others
UniRef100: UniRef100_Q6NZH9
UniRef90: UniRef90_Q6NZH9
UniRef50: UniRef50_Q8IV61
UniGene: Mm.329203

全选

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研究热度

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