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240087 Mdc1

240087

Mdc1

mediator of DNA damage checkpoint 1

protein-coding

Mus musculus

基因描述

Type Description
Definition mediator of DNA damage checkpoint 1

研究结论

Date Results Publications
2019-10-26 10:12:00 Mdc1 was dispensable for the synapsis of the autosomes and played only a minor role in X-Y synapsis, compared with the action of H2afx. 29437857
2019-03-09 11:33:00 Low MDC1 expression promotes invasion and metastasis of pancreatic ductal adenocarcinoma. 29059173
2017-05-13 22:24:00 MDC1 plays a fundamentally significant role in maintenance of genomic stability through a DNA damage response-independent pathway. 28193847
2016-04-16 10:36:00 MDC1 silencing enhances the radiosensitivity of human nasopharyngeal cancer CNE1 cells and results in xenograft tumor growth inhibition. 26247734
2012-05-12 11:51:00 oligomerization of MDC1 plays an important role in DDR and help understand the formation of proteins complexes at the sites of DNA damage. 21705321

名称对应

Type IDs
Synonymous 6820401C03, AA413496, Nfbd1, mKIAA0170
Gene
UniProtKB-ID: MDC1_MOUSE, E9QK89_MOUSE
UniprotKB: Q5PSV9, E9QK89
UniParc: UPI0000D67D4F, UPI0000498003
EMBL: BC085140, AY826432, CR974451, AK129074, BC094363
Ensembl: ENSMUSG00000061607
KO: mmu:240087
Nucleutide sequences
EMBL-CDS: AAH94363.1, AAV85449.1, AAH85140.1, BAC97884.1
Ensembl_TRS: ENSMUST00000082337
Protein sequencees
Ensembl_PRO: ENSMUSP00000080949
RefSeq: XP_006524327.1, XP_006524325.1, XP_006524324.1, NP_001010833.2, XP_030105659.1, XP_006524323.1, XP_006524326.1
Others
UniRef100: UniRef100_Q5PSV9, UniRef100_E9QK89
UniRef90: UniRef90_Q5PSV9
UniRef50: UniRef50_Q5PSV9
UniGene: Mm.218511

全选

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