| Type | Description |
|---|---|
| Definition | leucyl/cystinyl aminopeptidase |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:07:00 | Insulin-regulated aminopeptidase deficiency impairs cardiovascular adaptations and placental development during pregnancy. | 33252660 |
| 2020-08-29 12:48:00 | IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses. | 32487999 |
| 2020-01-11 10:41:00 | IRAP, similar to Glut4 and sortilin, is retrieved from endosomes to the trans-Golgi network by retromer. | 30943117 |
| 2018-02-17 10:56:00 | Significant role for IRAP in postnatal brain development and normal function of the hippocampus in adulthood. | 27713012 |
| 2017-05-06 20:36:00 | this paper shows that endosomal retention of TLR9 via the interaction of IRAP with the actin cytoskeleton is a mechanism that prevents hyper-activation of TLR9 in dendritic cells | 28319098 |
| Type | IDs |
|---|---|
| Synonymous | 2010309L07Rik, 4732490P18Rik, CAP, IRAP, PLAP, gp160, vp165 |
| Gene |
UniProtKB-ID:
LCAP_MOUSE
UniprotKB:
Q8C129
UniParc:
UPI000002750F
EMBL:
BC120925,
BC120926,
AK029094
Ensembl:
ENSMUSG00000023845
KO:
mmu:240028
|
| Nucleutide sequences |
EMBL-CDS:
BAC26293.1,
AAI20926.1,
AAI20927.1
Ensembl_TRS:
ENSMUST00000041047
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000036998
RefSeq:
XP_036016480.1,
NP_766415.1
|
| Others |
UniRef100:
UniRef100_Q8C129
UniRef90:
UniRef90_P97629
UniRef50:
UniRef50_Q9UIQ6
UniGene:
Mm.328807,
Mm.393452
CCDS:
CCDS37457.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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