| Type | Description |
|---|---|
| Definition | protein kinase, interferon inducible double stranded RNA dependent activator |
| Date | Results | Publications |
|---|---|---|
| 2020-05-02 11:33:00 | PACT enhances mammalian embryonic neural stem cell properties as assessed in vitro and in vivo. PACT augments the Notch signaling pathway, a master regulator of neural stem cell fate, at the transcriptional level. | 30967258 |
| 2018-10-06 10:52:00 | TARBP2, but not PRKRA, functions in miRNA biogenesis of a subclass of miRNAs, and suggesting that functional redundancy between TARBP2 and PRKRA does not involve miRNA biogenesis. | 29467169 |
| 2018-08-11 11:27:00 | PKR knock-out alleviates abnormal brain signaling and body weight gain in experimental obesity. | 29795582 |
| 2017-11-26 00:38:00 | PACT interacts with LGP2 and this interaction is enhanced by encephalomyocarditis virus (EMCV) infection. In vitro interaction analyses using purified recombinant proteins confirmed that the single-stranded Theiler's murine encephalitis virus genome enhanced the interaction between LGP2 and PACT. | 29032202 |
| 2016-05-28 12:16:00 | Data (including data from studies in transgenic/knockout mice) suggest that PACT/RAX (protein activator of protein kinase R) functions as negative regulator of PKR/Eif2ak2 (protein kinase R) in development of postnatal anterior pituitary tissue. | 26414443 |
| Type | IDs |
|---|---|
| Synonymous | AV120107, PRK, Pact, RAX, lear |
| Gene |
UniProtKB-ID:
PRKRA_MOUSE
UniprotKB:
Q9WTX2
UniParc:
UPI0000020C8D
EMBL:
AK155112,
AK012798,
AF083032,
BC011311
Ensembl:
ENSMUSG00000002731
KO:
mmu:23992
|
| Nucleutide sequences |
EMBL-CDS:
AAH11311.1,
BAE33056.1,
BAB28477.1,
AAD33098.1
Ensembl_TRS:
ENSMUST00000002808
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000002808
RefSeq:
XP_017173512.1,
XP_030106795.1,
XP_030106794.1,
NP_036001.1
|
| Others |
UniRef100:
UniRef100_Q9WTX2
UniRef90:
UniRef90_Q9WTX2
UniRef50:
UniRef50_Q9WTX2
UniGene:
Mm.277250
CCDS:
CCDS16159.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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