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23991 Cib1

23991

Cib1

calcium and integrin binding 1 (calmyrin)

protein-coding

Mus musculus

基因描述

Type Description
Definition calcium and integrin binding 1 (calmyrin)

研究结论

Date Results Publications
2021-03-13 13:18:00 Expression of a TMC6-TMC8-CIB1 heterotrimeric complex in lymphocytes is regulated by each of the components. 32917726
2021-01-23 12:57:00 Identification of calcium and integrin-binding protein 1 as a novel regulator of production of amyloid beta peptide using CRISPR/Cas9-based screening system. 32307772
2019-07-20 12:37:00 Study shows that Cib1 negatively regulates degeneration of dopaminergic neurons in a mouse model of Parkinson's disease using 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Cib1 physically associated with apoptosis signal-regulating kinase 1 (Ask1) and thereby inhibited the 1-methyl-4-phenylpyrinidium-induced stimulation of the Ask1-mediated signaling cascade. 28939911
2018-09-22 11:47:00 mouse erythrocyte calmyrin is an interacting molecule of the rodent malaria parasite Plasmodium yoelii RhopH complex. 29653104
2017-09-23 11:19:00 results suggest that interaction of CIB1 with alphaIIb is one of the early events occurring during outside-in signaling. Furthermore, CIB1 recruits FAK to the alphaIIbbeta3 complex at the filopodia where FAK is activated, which in turn activates c-Src, resulting in propagation of outside-in signaling leading to platelet spreading. 28542214

名称对应

Type IDs
Synonymous Cibkip, Kip, Prkdcip
Gene
UniProtKB-ID: CIB1_MOUSE, Q8C2K4_MOUSE, A0A0U1RPF3_MOUSE
UniprotKB: Q9Z0F4, Q8C2K4, A0A0U1RPF3
UniParc: UPI000154A74D, UPI000000184B, UPI00000EA044
EMBL: AK027915, BC003714, AK165472, AF173010, AC109232, AK152805, AB006463, AK088450, BC054385, AB017361, AK010345
Ensembl: ENSMUSG00000030538
KO: mmu:23991
Nucleutide sequences
EMBL-CDS: AAG38960.1, BAC25663.1, AAH54385.1, BAE31510.1, BAA74429.1, BAE38209.1, BAB26868.1, BAA36165.1, AAH03714.1, BAC40359.1
Ensembl_TRS: ENSMUST00000065163, ENSMUST00000071457, ENSMUST00000206084
Protein sequencees
Ensembl_PRO: ENSMUSP00000070901, ENSMUSP00000071401, ENSMUSP00000145961
RefSeq: XP_011249163.1, NP_001278204.1, XP_030098413.1, NP_001278205.1, NP_036000.1
Others
UniRef100: UniRef100_Q9Z0F4, UniRef100_Q8C2K4, UniRef100_A0A0U1RPF3
UniRef90: UniRef90_Q8C2K4, UniRef90_Q9Z0F4, UniRef90_Q9R010
UniRef50: UniRef50_Q99828-2, UniRef50_B0VXW3, UniRef50_Q9R010
UniGene: Mm.30217
CCDS: CCDS21392.1

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