| Type | Description |
|---|---|
| Definition | myocardin related transcription factor B |
| Date | Results | Publications |
|---|---|---|
| 2020-04-25 12:43:00 | Knockout of Mrtfb in mouse intestine significantly enhances tumor development in Apc mutant mice. | 31690663 |
| 2019-10-05 10:28:00 | MRTF-A/B control an acute mechanosensitive signaling circuit that coordinates cross-talk between the actin and microtubule cytoskeleton and maintains intercalated disc integrity and cardiomyocyte homeostasis in heart disease. | 29716942 |
| 2019-07-13 12:28:00 | In conclusion, SRF andMKL1/MKL2 are essential for postnatal podocyte structure and function, likely through the maintenance of a normal actin cytoskeleton. | 29114040 |
| 2017-09-09 11:26:00 | BRG1 promotes transcription of endothelial Mrtfa and Mrtfb, which elevates expression of SRF and SRF target genes that establish embryonic capillary integrity. | 28729363 |
| 2016-03-26 10:38:00 | MRTF-A/B depletion results in an increase in the cell surface expression of ICAM-1 and interactions between HAoECs and leukocytes | 26024305 |
| Type | IDs |
|---|---|
| Synonymous | Gt4-1, MRTF-B, Mkl2, mKIAA1243 |
| Gene |
UniProtKB-ID:
MRTFB_MOUSE,
Q8R2L3_MOUSE,
G3X8R8_MOUSE,
Q5DTZ3_MOUSE
UniprotKB:
P59759,
Q8R2L3,
G3X8R8,
Q5DTZ3
UniParc:
UPI00001EA3B8,
UPI00004E16E9,
UPI0000001725,
UPI0000028072
EMBL:
BC028459,
AF532598,
BC131644,
AC163640,
AK220377,
AC160961
Ensembl:
ENSMUSG00000009569
KO:
mmu:239719
|
| Nucleutide sequences |
EMBL-CDS:
AAN33042.1,
AAH28459.1,
BAD90435.1,
AAI31645.1
Ensembl_TRS:
ENSMUST00000056715,
ENSMUST00000115809,
ENSMUST00000009713,
ENSMUST00000149359
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000054993,
ENSMUSP00000111476,
ENSMUSP00000009713,
ENSMUSP00000122815
RefSeq:
XP_006522171.1,
NP_705816.2,
XP_030104965.1,
XP_006522172.1,
NP_001116139.1,
NP_862908.1,
XP_030104966.1,
XP_006522174.1,
XP_030104964.1,
XP_036015810.1
|
| Others |
UniRef100:
UniRef100_Q8R2L3,
UniRef100_Q5DTZ3,
UniRef100_P59759,
UniRef100_G3X8R8
UniRef90:
UniRef90_D3ZN80,
UniRef90_P59759
UniRef50:
UniRef50_D3ZN80,
UniRef50_P59759
UniGene:
Mm.270643
CCDS:
CCDS37258.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员