| Type | Description |
|---|---|
| Definition | NLR family, pyrin domain containing 5 |
| Date | Results | Publications |
|---|---|---|
| 2016-12-17 10:12:00 | The expression of Mater protein is decreased in mature oocytes from old versus young mice. | 26769260 |
| 2015-07-25 10:03:00 | MATER is part of the subcortical maternal complex (SCMC). SCMC is required for formation of the cytoplasmic F-actin meshwork that controls the central position of the spindle and ensures symmetric division. | 25208553 |
| 2014-03-29 11:15:00 | MATER is required for endoplasmic reticulum distribution and Ca2+ homeostasis in oocytes, likely due to defects in lattice-mediated ER positioning and/or redistribution. | 24374158 |
| 2012-09-22 11:16:00 | It was concluded that lack of Nlrp5 in oocytes triggers premature activation of the mitochondrial pool, causing mitochondrial damage that cannot be rescued by inactivation of Bax. | 22357545 |
| 2011-11-26 10:37:00 | Transgenic expression of MATER induces antigen-specific tolerance with a significant reduction in ovarian autoimmunity. | 21447630 |
| Type | IDs |
|---|---|
| Synonymous | Mater, Nalp5, Op1, PAN11 |
| Gene |
UniProtKB-ID:
NALP5_MOUSE
UniprotKB:
Q9R1M5
UniParc:
UPI00014F7AE4,
UPI000023048B,
UPI00014F7AE8,
UPI00014F7AE6,
UPI0000230491,
UPI00014F7AE9,
UPI0000021410,
UPI00014F7AE7
EMBL:
AF143573,
AY329489,
BC053384,
AY196361,
AF143565,
AF143563,
AF143572,
AF143564,
AY329490,
AF143568,
AY329484,
AY329486,
AK135731,
AY329488,
AY329487,
AY329491,
AF074018,
AF143566,
AF143559,
AF143571,
AF143569,
AY329485,
AF143567,
AF143561,
AY196362,
AF143562,
AF143560,
AF143570
Ensembl:
ENSMUSG00000015721
KO:
mmu:23968
|
| Nucleutide sequences |
EMBL-CDS:
AAQ94609.1,
AAQ94612.1,
AAQ94610.1,
AAD51762.1,
AAO52698.1,
AAQ94613.1,
AAO52697.1,
AAQ94607.1,
AAQ94614.1,
BAE22633.1,
AAH53384.1,
AAQ94611.1,
AAF64393.1,
AAQ94608.1
Ensembl_TRS:
ENSMUST00000108441,
ENSMUST00000133237,
ENSMUST00000015866,
ENSMUST00000086341,
ENSMUST00000139661
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000083524,
ENSMUSP00000122007,
ENSMUSP00000104080,
ENSMUSP00000118638,
ENSMUSP00000015866
RefSeq:
NP_035990.1,
NP_001292786.1,
NP_001034232.1
|
| Others |
UniRef100:
UniRef100_Q9R1M5
UniRef90:
UniRef90_Q9R1M5
UniRef50:
UniRef50_Q9R1M5
UniGene:
Mm.333653
CCDS:
CCDS20929.1,
CCDS20930.1,
CCDS85233.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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