| Type | Description |
|---|---|
| Definition | nuclear receptor subfamily 0, group B, member 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-05 13:55:00 | Disruption of hepatic small heterodimer partner induces dissociation of steatosis and inflammation in experimental nonalcoholic steatohepatitis. | 31831621 |
| 2020-07-04 10:58:00 | Upon virus infection, SHP interacts specifically with CREB-binding protein (CBP) in the nucleus, thereby obstructing CBP/beta-catenin interaction competitively. | 31091449 |
| 2019-12-07 10:05:00 | This study demonstrates that expression and activity of SHP within macrophages can alter T cell fate and identifies SHP as a potential therapeutic target for autoimmune diseases or solid cancers. | 31050726 |
| 2019-11-09 11:36:00 | SHP regulates Cxcl2 transcription in hepatocytes, playing a pivotal role in the recruitment of neutrophils. SHP-targeting strategies may represent alternative approaches to control fulminant hepatitis | 30323351 |
| 2019-10-26 12:29:00 | Shp regulates morphine withdrawal syndrome via modulation of Ugt2b expression. | 30689982 |
| Type | IDs |
|---|---|
| Synonymous | SHP, SHP-1, Shp1 |
| Gene |
UniProtKB-ID:
NR0B2_MOUSE
UniprotKB:
Q62227
UniParc:
UPI0000001989
EMBL:
AY360324,
AY360323,
BC019540,
L76567
Ensembl:
ENSMUSG00000037583
KO:
mmu:23957
|
| Nucleutide sequences |
EMBL-CDS:
AAQ55057.1,
AAB59732.1,
AAH19540.1,
AAQ55058.1
Ensembl_TRS:
ENSMUST00000042706
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000039175
RefSeq:
NP_035980.1
|
| Others |
UniRef100:
UniRef100_Q62227
UniRef90:
UniRef90_Q62227
UniRef50:
UniRef50_Q62227
UniGene:
Mm.346759
CCDS:
CCDS18751.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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