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239528 Ago2

239528

Ago2

argonaute RISC catalytic subunit 2

protein-coding

Mus musculus

基因描述

Type Description
Definition argonaute RISC catalytic subunit 2

研究结论

Date Results Publications
2020-08-22 15:28:00 An essential role for Argonaute 2 in EGFR-KRAS signaling in pancreatic cancer development. 32499547
2020-03-21 12:16:00 Data suggest that miRNA-1224-mediated and Ago2-dependent modulation of spinal circRNA-Filip1l expression regulates nociception via targeting Ubr5, revealing a novel epigenetic mechanism of interaction between miRNA and circRNA in chronic inflammation pain. 30651325
2020-03-21 10:34:00 The N-terminus of MOV10 also leads to increased RGG box-dependent binding to the SC1 RNA G-Quadruplex and is required for outgrowth of neurites. Lastly, we showed that FMRP has a global role in miRNA-mediated translational regulation by recruiting AGO2 to a large subset of RNAs in mouse brain. 31740951
2020-02-01 10:49:00 High-Throughput Analysis Reveals Rules for Target RNA Binding and Cleavage by AGO2. 31324449
2020-01-11 12:51:00 Reporter assays suggest that the 3'-UTRs of several FAM120A-bound miRNA target genes are less sensitive to Ago2-mediated target repression than those of FAM120A-unbound miRNA targets and FAM120A modulates them via its G-rich target sites 31289130

名称对应

Type IDs
Synonymous 1110029L17Rik, 2310051F07Rik, AI225898, AL022874, AW546247, Eif2c2, Gerp95, Gm10365, mKIAA4215
Gene
UniProtKB-ID: AGO2_MOUSE, Q3UQ34_MOUSE
UniprotKB: Q8CJG0, Q3UQ34
UniParc: UPI0000EA30FC, UPI00005AC184
EMBL: AK142854, BC128379, BC096465, AB081472, AK220193, BC129922
Ensembl: ENSMUSG00000036698
KO: mmu:239528
Nucleutide sequences
EMBL-CDS: AAH96465.1, AAI28380.1, AAI29923.1, BAC15767.1, BAD90378.1, BAE25210.1
Ensembl_TRS: ENSMUST00000044113
Protein sequencees
Ensembl_PRO: ENSMUSP00000042207
RefSeq: NP_694818.3
Others
UniRef100: UniRef100_Q8CJG0, UniRef100_Q3UQ34
UniRef90: UniRef90_Q3UQ34, UniRef90_Q8CJG0
UniRef50: UniRef50_Q3UQ34, UniRef50_Q9UKV8
UniGene: Mm.23095, Mm.391971, Mm.440409, Mm.476931, Mm.486474, Mm.490340
CCDS: CCDS37098.1

全选

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