| Type | Description |
|---|---|
| Definition | solute carrier family 30 (zinc transporter), member 8 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:44:00 | Effects of ZnT8 on epithelial-to-mesenchymal transition and tubulointerstitial fibrosis in diabetic kidney disease. | 32681069 |
| 2020-04-04 11:35:00 | ZnT8 haploinsufficiency is associated with downregulation of mRNAs for Slc39a8 and Slc39a14 and with lowered total cellular zinc content in MIN6 cells. | 31690008 |
| 2019-12-28 10:38:00 | Study revealed an unexpected role of ZnT8 in regulating peripheral 5-HT biogenesis and intestinal microenvironment, which might contribute to the increased risk of obesity and type 2 diabetes. | 30936149 |
| 2019-05-11 10:56:00 | provided the first evidence that ZnT8 transports Zn into Leydig cell mitochondria with gonadotropin stimulation and suggests that ZnT8 may play a role in testosterone production via the signaling pathway | 30236453 |
| 2019-05-04 12:18:00 | Zinc Transporter 8 (ZnT8) shRNA attenuates specific CD8+ T cell activation and cytotoxicity. ZnT8 shRNA protects glucose tolerance and pancreatic tissue injury via down-regulation of ZnT8 in NOD mice. | 29601938 |
| Type | IDs |
|---|---|
| Synonymous | C820002P14Rik, ZnT-8, ZnT8 |
| Gene |
UniProtKB-ID:
ZNT8_MOUSE
UniprotKB:
Q8BGG0
UniParc:
UPI00000274F5
EMBL:
BC117544,
AK050482,
BC118521,
AK050494
Ensembl:
ENSMUSG00000022315
KO:
mmu:239436
|
| Nucleutide sequences |
EMBL-CDS:
BAC34281.1,
AAI17545.1,
AAI18522.1,
BAC34289.1
Ensembl_TRS:
ENSMUST00000037240
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000035257
RefSeq:
NP_766404.1
|
| Others |
UniRef100:
UniRef100_Q8BGG0
UniRef90:
UniRef90_P0CE46
UniRef50:
UniRef50_Q8IWU4
UniGene:
Mm.208831
CCDS:
CCDS27464.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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