| Type | Description |
|---|---|
| Definition | R-spondin 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:03:00 | R-spondin 2 mediates neutrophil egress into the alveolar space through increased lung permeability. | 32019591 |
| 2019-10-26 12:12:00 | These results suggest that SMN-derived Rspo2 plays a major role in AChR clustering and NMJ formation in the postsynaptic region, and muscle-derived Rspo2 also plays a substantial role in juxtaposition of the active zones and synaptic folds. | 30206360 |
| 2019-09-21 12:27:00 | RSPO2, but not SPON1, specifically promoted the differentiation of midbrain dopaminergic (mDA) neuroblasts into mDA neurons in mouse primary cultures and embryonic stem cells (ESCs). | 30146491 |
| 2019-01-05 12:13:00 | Rspo2 and Rspo3 fusion events are sufficient to initiate hyperplasia and tumour development. | 28695896 |
| 2018-05-12 10:53:00 | Data report that Rspo2, is highly expressed in the spinal motor neuron (SMN) and binds to its receptor Lgr5, at the neuromuscular junction (NMJ). Rspo2 enhances the LRP4/MuSK signaling via Lgr5 in an agrin-independent manner and promotes AChR clustering. In addition, the loss of Rspo2 in mice compromises AChR clustering, the ultrastructure of the NMJ, and neuromuscular signal transduction. | 27328992 |
| Type | IDs |
|---|---|
| Synonymous | 2610028F08Rik, AA673245, D430027K22, ftls |
| Gene |
UniProtKB-ID:
RSPO2_MOUSE
UniprotKB:
Q8BFU0
UniParc:
UPI00000274F4
EMBL:
BC052844,
AK087485,
AK049891
Ensembl:
ENSMUSG00000051920
KO:
mmu:239405
|
| Nucleutide sequences |
EMBL-CDS:
BAC33974.1,
BAC39893.1
Ensembl_TRS:
ENSMUST00000063492,
ENSMUST00000226810
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000154600,
ENSMUSP00000067325
RefSeq:
XP_030104398.2,
XP_011243911.2,
XP_011243909.1,
XP_036015287.1,
NP_766403.1,
NP_001344885.1,
XP_036015286.1,
NP_001344886.1,
XP_017172085.2
|
| Others |
UniRef100:
UniRef100_Q8BFU0
UniRef90:
UniRef90_Q6UXX9
UniRef50:
UniRef50_Q6UXX9
UniGene:
Mm.193274
CCDS:
CCDS27451.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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