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239337 Adamts12

239337

Adamts12

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12

protein-coding

Mus musculus

基因描述

Type Description
Definition a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12

研究结论

Date Results Publications
2020-09-12 16:03:00 Identification of relevant genetic alterations in cancer using topological data analysis. 32732999
2019-11-30 12:28:00 Adamts7-/- Adamts12-/- mice, but not corresponding single-gene mutants, develop progressive heterotopic ossification (HO) in tendons with abnormal collagen fibrils, accompanied by reduced levels of the small leucine-rich proteoglycans which regulate collagen fibrillogenesis. These results suggest that Adamts7 and Adamts12 drive an innate pathway protective against hindlimb HO in mice. 29618652
2019-07-27 13:06:00 This study provides evidence that ADAMTS-12 is a critical regulator of inflammatory arthritis and that this is mediated, at least in part, through control of CTGF turnover. 29750395
2015-02-14 11:32:00 ADAMTS-12 is a multifaced metalloproteinase in arthritis and inflammation [review] 24876675
2013-02-23 10:04:00 ADAMTS-12 is implicated in the inflammatory response by modulating normal neutrophil apoptosis. 23019333

名称对应

Type IDs
Synonymous ADAMTS-12, AI605170
Gene
UniProtKB-ID: ATS12_MOUSE, Q3UXR3_MOUSE, Q8BMS3_MOUSE
UniprotKB: Q811B3, Q3UXR3, Q8BMS3
UniParc: UPI00005ABB7F, UPI0000D8B078, UPI00000EB5DE, UPI00000EB2D0
EMBL: AK028812, AC102219, AC156609, AC159963, AK135354, AJ537452, AK048612, AK054015
Ensembl: ENSMUSG00000047497
KO: mmu:239337
Nucleutide sequences
EMBL-CDS: BAC33391.1, BAC35621.1, CAD60967.1, BAE22500.1, BAC26131.1
Ensembl_TRS: ENSMUST00000061318
Protein sequencees
Ensembl_PRO: ENSMUSP00000057796
RefSeq: XP_036015283.1, XP_036015284.1, XP_036015285.1, NP_780710.2
Others
UniRef100: UniRef100_Q811B3, UniRef100_Q3UXR3
UniRef90: UniRef90_Q811B3, UniRef90_Q3UXR3
UniRef50: UniRef50_Q3UXR3, UniRef50_P58397
UniGene: Mm.482727
CCDS: CCDS27384.1

全选

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