CARD6 protects against collagen-induced rheumatoid arthritis in mice through attenuating the inflammatory response and joint destruction via suppression of TNFR1/TRAF2 signaling.

Biochem Biophys Res Commun     Min Zhao , Hongying He , Jianbao Yin

Increased macrophage activation mediated by caspase recruitment domain 6 knockdown through negatively targeting AMPK.

Biochem Biophys Res Commun     Fangyuan Chen , Juanli Li , Gang Tian , Zuyi Yuan

Targeting CARD6 attenuates spinal cord injury (SCI) in mice through inhibiting apoptosis, inflammation and oxidative stress associated ROS production.

Aging (Albany NY)     Jiang Lin Wang , Xiao Luo , Li Liu

Caspase Recruitment Domain Protein 6 Protects Against Hepatic Steatosis and Insulin Resistance by Suppressing Apoptosis Signal-Regulating Kinase 1.

Hepatology     Peng Sun , Qiang Zeng , Daqing Cheng , Kuo Zhang , Jilin Zheng , Yupeng Liu , Yu-Feng Yuan , Yi-Da Tang

Caspase recruitment domain 6 protects against hepatic ischemia/reperfusion injury by suppressing ASK1.

J. Hepatol.     Juan-Juan Qin , Wenzhe Mao , Xiaozhan Wang , Peng Sun , Daqing Cheng , Song Tian , Xue-Yong Zhu , Ling Yang , Zan Huang , Hongliang Li

Caspase recruitment domain 6 protects against cardiac hypertrophy in response to pressure overload.

Hypertension     Liangpeng Li , Wen Chen , Yifan Zhu , Xiaodi Wang , Ding-Sheng Jiang , Fuhua Huang , Liming Wang , Fei Xiang , Wei Qin , Qiang Wang , Rui Zhang , Xueyong Zhu , Hongliang Li , Xin Chen

A high-resolution anatomical atlas of the transcriptome in the mouse embryo.

PLoS Biol.     Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio

CARD6 is interferon inducible but not involved in nucleotide-binding oligomerization domain protein signaling leading to NF-kappaB activation.

Mol. Cell. Biol.     Almut Dufner , Gordon S Duncan , Andrew Wakeham , Alisha R Elford , HÃ¥kan T Hall , Pamela S Ohashi , Tak W Mak

Caspase recruitment domain protein 6 is a microtubule-interacting protein that positively modulates NF-kappaB activation.

Proc. Natl. Acad. Sci. U.S.A.     Almut Dufner , Scott Pownall , Tak W Mak

Antisense transcription in the mammalian transcriptome.

Science     S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G Engström , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium