| Type | Description |
|---|---|
| Definition | katanin p60 (ATPase-containing) subunit A1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 11:52:00 | Study uncovered an unexpected role of the p60-MIT and p80-CTD domains of katanin in the oligomerization and regulation of the protein. p80-CTD mediates the assembly of p60-MIT:p80-CTD heterodimers into heterotetramers that have an impact on katanin MT end and lattice binding as well as on the severing activity of the enzyme. The heterotetrameric structure of the p60-MIT:p80-CTD K555A/R591A mutant revealed a domain swap. | 31353241 |
| 2019-07-20 11:52:00 | This study structurally and functionally characterized the interaction between the two katanin subunits that is mediated by the p60-MIT domain and the p80 C-terminal domain (p80-CTD). p60-MIT and p80-CTD form a tight heterodimeric complex, whose high-resolution structure was determined by X-ray crystallography. | 29097679 |
| 2010-10-23 11:04:00 | Our results suggest that LECT2 regulates neuritic extension through microtubular morphallaxis through the control of katanin-P60 levels. | 20463617 |
| 2010-06-28 12:08:00 | A common substrate recognition mode conserved between katanin p60 and VPS4 governs microtubule severing and membrane skeleton reorganization | 20339000 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
E9PZI6_MOUSE
UniprotKB:
E9PZI6
UniParc:
UPI0001B1A4CB
EMBL:
AC156391
Ensembl:
ENSMUSG00000019794
KO:
mmu:23924
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000165806
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000132514
RefSeq:
NP_035965.2,
XP_030100951.1,
XP_036011678.1
|
| Others |
UniRef100:
UniRef100_E9PZI6
UniRef90:
UniRef90_Q9WV86
UniRef50:
UniRef50_Q9BW62
UniGene:
Mm.28127,
Mm.421297
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
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