| Type | Description |
|---|---|
| Definition | arachidonate 12-lipoxygenase, 12S type |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:28:00 | The Investigation of Lipoxygenases as Therapeutic Targets in Malignant Pleural Mesothelioma. | 30941737 |
| 2021-01-23 12:57:00 | Biosynthesis of the Maresin Intermediate, 13S,14S-Epoxy-DHA, by Human 15-Lipoxygenase and 12-Lipoxygenase and Its Regulation through Negative | 32324389 |
| 2020-12-26 13:11:00 | Arachidonate 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid contribute to stromal aging-induced progression of pancreatic cancer. | 32265301 |
| 2020-12-19 13:39:00 | 12-LOX catalyzes the oxidation of 2-arachidonoyl-lysolipids in platelets generating eicosanoid-lysolipids that are attenuated by iPLA2gamma knockout. | 32161117 |
| 2020-10-24 14:04:00 | Inhibition of arachidonate lipoxygenase12 targets lung cancer through inhibiting EMT and suppressing RhoA and NF-kappaB activity. | 32037090 |
| Type | IDs |
|---|---|
| Synonymous | 12-LOX, 12S-LOX, LOG12 |
| Gene |
UniProtKB-ID:
LOX12_HUMAN
UniprotKB:
P18054
UniParc:
UPI000013CD03
EMBL:
AY527817,
M87004,
AF143883,
M35418,
S68587,
AC040977,
M62982,
D12638,
BC069557,
M58704
Ensembl:
ENSG00000108839
KO:
hsa:239
|
| Nucleutide sequences |
EMBL-CDS:
AAH69557.1,
AAD14020.1,
AAD32700.1,
AAA51533.1,
AAA60056.1,
AAA51587.1,
BAA02162.1,
AAS00094.1,
AAA59523.1
Ensembl_TRS:
ENST00000251535
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000251535
RefSeq:
NP_000688.2,
XP_011522082.1
|
| Others |
UniRef100:
UniRef100_P18054
UniRef90:
UniRef90_P18054
UniRef50:
UniRef50_P18054
UniGene:
Hs.654431
CCDS:
CCDS11084.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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