| Type | Description |
|---|---|
| Definition | gremlin 2, DAN family BMP antagonist |
| Date | Results | Publications |
|---|---|---|
| 2018-07-28 11:40:00 | Grem2 knockdown inhibited cardiomyocyte differentiation, and this effect was similar to that of Notch1 pathway inhibition in vitro. Grem2 enhances the protective effect of cardiac progenitor cells on heart function in a mouse model of myocardial infarction. | 29794428 |
| 2017-05-06 20:37:00 | Grem2 provides a molecular barrier that controls the extent of inflammatory cell infiltration by suppressing BMP2 after myocardial infarction. | 27283840 |
| 2015-02-14 11:42:00 | Grem2 expression is regulated during development and embryonic stem cell differentiation. | 24648383 |
| 2014-02-22 10:56:00 | PRDC binds heparin with high affinity and that heparin binding to PRDC interferes with BMP antagonism. | 23850456 |
| 2013-07-06 10:02:00 | We show that Tbx2 directly represses Grem1 in distal regions of the posterior limb mesenchyme allowing Bone morphogenetic protein (Bmp) signaling to abrogate Fgf4/9/17 expression in the overlying epithelium. | 23633963 |
| Type | IDs |
|---|---|
| Synonymous | Gremlin2, Prdc |
| Gene |
UniProtKB-ID:
GREM2_MOUSE,
Q3TST1_MOUSE
UniprotKB:
O88273,
Q3TST1
UniParc:
UPI0000024F27
EMBL:
BC079905,
AK161827,
AB011030,
AK142008
Ensembl:
ENSMUSG00000050069
KO:
mmu:23893
|
| Nucleutide sequences |
EMBL-CDS:
AAH79905.1,
BAA29038.1,
BAE36594.1,
BAE24912.1
Ensembl_TRS:
ENSMUST00000055294
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000049640
RefSeq:
NP_035955.1,
XP_036020540.1,
XP_036020541.1,
XP_006496889.1
|
| Others |
UniRef100:
UniRef100_O88273
UniRef90:
UniRef90_O88273
UniRef50:
UniRef50_O88273
UniGene:
Mm.25760
CCDS:
CCDS15545.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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