| Type | Description |
|---|---|
| Definition | gremlin 1, DAN family BMP antagonist |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:06:00 | Gremlin 1 depletion in vivo causes severe enteropathy and bone marrow failure. | 32297672 |
| 2020-08-13 18:51:00 | Down-regulation of Gremlin1 inhibits inflammatory response and vascular permeability in chronic idiopathic urticaria through suppression of TGF-beta signaling pathway. | 32580008 |
| 2020-07-18 12:23:00 | GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients | 31694641 |
| 2018-08-04 12:05:00 | remlin can aggravate podocyte lesions through the TGF-beta signaling pathway. | 29315280 |
| 2018-03-10 12:03:00 | We conclude that gremlin promotes RPE cell proliferation, migration and VEGF production possibly via activating VEGFR2-Akt-mTORC2 signaling. Gremlin could be a novel therapeutic target of ROP or other retinal vasoproliferation diseases. | 27894090 |
| Type | IDs |
|---|---|
| Synonymous | Cktsf1b1, Drm, Grem, ld |
| Gene |
UniProtKB-ID:
GREM1_MOUSE,
Q3TNY7_MOUSE
UniprotKB:
O70326,
Q3TNY7
UniParc:
UPI0000024E21
EMBL:
AF108189,
BC015293,
AF045801,
AK164871,
AK157793
Ensembl:
ENSMUSG00000074934
KO:
mmu:23892
|
| Nucleutide sequences |
EMBL-CDS:
AAD54056.1,
AAC40111.1,
AAH15293.1,
BAE34201.1,
BAE37950.1
Ensembl_TRS:
ENSMUST00000099575
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000097170
RefSeq:
NP_035954.1
|
| Others |
UniRef100:
UniRef100_O70326
UniRef90:
UniRef90_O70326
UniRef50:
UniRef50_O60565
UniGene:
Mm.166318
CCDS:
CCDS16560.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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