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238871 Pde4d

238871

Pde4d

phosphodiesterase 4D, cAMP specific

protein-coding

Mus musculus

基因描述

Type Description
Definition phosphodiesterase 4D, cAMP specific

研究结论

Date Results Publications
2021-02-27 13:45:00 Dominant-Negative Attenuation of cAMP-Selective Phosphodiesterase PDE4D Action Affects Learning and Behavior. 32784895
2020-10-03 12:53:00 Upregulation of miR-219a-5p Decreases Cerebral In Vitro by Targeting Pde4d. 32249206
2020-06-20 12:35:00 Proteomics identified the PP2A regulatory subunit B55alpha as the factor recruiting PP2A to PDE4D5. The B55alpha-PP2A complex localized to adhesions and directly dephosphorylated PDE4D5. 31408443
2019-11-02 12:53:00 Long-term memory is enhanced by retrosplenial and hippocampal knockdown (KD) of the cAMP specific phosphodiesterase Pde4d. 29497131
2019-07-13 12:33:00 In vivo, the atropine-dependent prolongation of heart rate increase was blunted in PDE4D but not in wildtype or PDE4B knockout mice. The authors propose that inhibition of PDE4 by atropine accounts, at least in part, for the induction of tachycardia and the arrhythmogenic potency of this drug. 29123207

名称对应

Type IDs
Synonymous 9630011N22Rik, Dpde3
Gene
UniProtKB-ID: PDE4D_MOUSE, A6XDA7_MOUSE, A6XDB0_MOUSE, B2KF84_MOUSE, A2RSH1_MOUSE, E9PVU7_MOUSE
UniprotKB: Q01063, A6XDA7, A6XDB0, B2KF84, A2RSH1, E9PVU7
UniParc: UPI000173A8F4, UPI00000281F6, UPI00000E9D7C, UPI0000214E3D, UPI0001578270, UPI00001D67CA, UPI000173A8F6
EMBL: AC154376, CT030256, DQ665892, AC174458, CT025605, DQ665894, AC163650, CT025614, DQ665893, BC132107, BC132109, CT033775, AY388962, AC161585, AF536978, AC156571, AC154756, DQ665895, M94541, AC102805, AK081466, AC154792
Ensembl: ENSMUSG00000021699
KO: mmu:238871
Nucleutide sequences
EMBL-CDS: AAN10120.1, AAA37368.1, CAQ51656.1, BAC38226.1, AAQ90406.1, ABG57275.1, ABG57273.1, ABG57274.1, ABG57276.1, AAI32110.1, AAI32108.1
Ensembl_TRS: ENSMUST00000177907, ENSMUST00000122041, ENSMUST00000074103, ENSMUST00000120664, ENSMUST00000117420, ENSMUST00000119507, ENSMUST00000120671
Protein sequencees
Ensembl_PRO: ENSMUSP00000073742, ENSMUSP00000113488, ENSMUSP00000136485, ENSMUSP00000113024, ENSMUSP00000113610, ENSMUSP00000114089, ENSMUSP00000112991
RefSeq: XP_006517707.1, NP_035186.1, XP_006517712.1, XP_006517708.1, XP_030103122.1, XP_006517706.1, XP_006517711.1, XP_006517710.1
Others
UniRef100: UniRef100_Q01063, UniRef100_E9PVU7, UniRef100_A6XDB0, UniRef100_B2KF84
UniRef90: UniRef90_P14270, UniRef90_Q08499, UniRef90_P14270-4, UniRef90_A6XDB0
UniRef50: UniRef50_Q08499, UniRef50_P14270-4, UniRef50_P14270, UniRef50_P14270-2
UniGene: Mm.434429
CCDS: CCDS49359.1

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