| Type | Description |
|---|---|
| Definition | E26 avian leukemia oncogene 2, 3' domain |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:53:00 | Ets2 suppresses inflammatory cytokines through MAPK/NF-kappaB signaling and directly binds to the IL-6 promoter in macrophages. | 31785145 |
| 2020-09-05 13:57:00 | Protein C-ets-2 epigenetically suppresses TLRs-induced interleukin 6 production in macrophages. | 31810605 |
| 2020-07-11 12:08:00 | ETS2 is identified as a novel regulator of insulin production and a potential therapeutic target for diabetes mellitus treatment. | 31754329 |
| 2017-11-18 10:30:00 | Homozygous deletion of Ets2 in p53 mutant mice resulted in strong down-regulation of snoRNAs and reversed the prometastatic phenotype of mutant p53 but had no effect on osteosarcoma development, which remained 100% penetrant. | 29021240 |
| 2017-08-12 10:16:00 | These results suggest an unappreciated role for ETS2 in fibroblasts in establishing an immune-suppressive microenvironment in response to oncogenic Kras(G12D) signaling during the initial stages of tumor development. | 27659014 |
| Type | IDs |
|---|---|
| Synonymous | AU022856, Ets-2 |
| Gene |
UniProtKB-ID:
ETS2_MOUSE,
Q3UP99_MOUSE
UniprotKB:
P15037,
Q3UP99
UniParc:
UPI0000001885
EMBL:
BC005504,
AK153339,
AK038348,
J04103,
AK153478,
AK143687
Ensembl:
ENSMUSG00000022895
KO:
mmu:23872
|
| Nucleutide sequences |
EMBL-CDS:
AAH05504.1,
AAA37581.1,
BAE20535.1,
BAE25498.1,
BAE31917.1,
BAE32028.1
Ensembl_TRS:
ENSMUST00000023612
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023612
RefSeq:
NP_035939.3
|
| Others |
UniRef100:
UniRef100_P15037
UniRef90:
UniRef90_P15037
UniRef50:
UniRef50_P15037
UniGene:
Mm.290207
CCDS:
CCDS37412.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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