| Type | Description |
|---|---|
| Definition | DAN domain family member 5, BMP antagonist |
| Date | Results | Publications |
|---|---|---|
| 2015-11-07 10:25:00 | Cerl2 plays an important role during heart development. | 25033293 |
| 2013-09-21 12:37:00 | The consequent prolonged Nodal activity in the node by the absence of Cerl2 affects local Nodal expression and prolongs its expression in the lateral plate mesoderm. | 23544137 |
| 2013-06-08 12:40:00 | Decay of Cerl2 mRNA on the left is initiated by the leftward flow and further enhanced by the operation of Wnt-Cerl2 interlinked feedback loops. | 23271656 |
| 2012-11-24 10:38:00 | Study shows the cilia protein Arl13b is required for left right axis specification as its absence results in heterotaxia; the defect originates in the node where Cerl2 is not downregulated and asymmetric expression of Nodal is not maintained resulting in symmetric expression of both genes. | 22554696 |
| 2010-01-21 00:00:00 | Cerl-2 plays a key role in restricting the Nodal signaling pathway toward the left side of the mouse embryo by preventing its activity in the right side | 15466485 |
| Type | IDs |
|---|---|
| Synonymous | Cerl-2, Cerl2, Cerr2, Dte, GREM3, coco |
| Gene |
UniProtKB-ID:
DAND5_MOUSE,
Q3UPN3_MOUSE
UniprotKB:
Q76LW6,
Q3UPN3
UniParc:
UPI00005AC1E0,
UPI00001BDCC8
EMBL:
AB070694,
BC115659,
AY387409,
AK143395
Ensembl:
ENSMUSG00000053226
KO:
mmu:23863
|
| Nucleutide sequences |
EMBL-CDS:
AAI15660.1,
BAC82439.1,
AAR25615.1,
BAE25362.1
Ensembl_TRS:
ENSMUST00000065539
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000070057
RefSeq:
NP_957679.1
|
| Others |
UniRef100:
UniRef100_Q3UPN3,
UniRef100_Q76LW6
UniRef90:
UniRef90_Q76LW6,
UniRef90_Q3UPN3
UniRef50:
UniRef50_Q76LW6,
UniRef50_Q3UPN3
UniGene:
Mm.304252
CCDS:
CCDS22477.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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