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23859 Dlg2

23859

Dlg2

discs large MAGUK scaffold protein 2

protein-coding

Mus musculus

基因描述

Type Description
Definition discs large MAGUK scaffold protein 2

研究结论

Date Results Publications
2021-01-02 12:50:00 A DLG2 deficiency in mice leads to reduced sociability and increased repetitive behavior accompanied by aberrant synaptic transmission in the dorsal striatum. 32164788
2020-10-03 12:54:00 PIP3-Phldb2 is crucial for LTP regulating synaptic NMDA and AMPA receptor density and PSD95 turnover. 30867511
2020-05-30 13:54:00 PSD-93 is identified as a target gene of miR-152-3p. 31326116
2018-12-22 10:13:00 Study describe a novel splice variant of Dlg2 gene termed Dlg2eta and define the differential expression pattern of DLG2 isoforms in IFNbeta-producing plasmacytoid dendritic cells (pDCs). The presence of DLG2eta protein in the CNS of Dlg2 mice might influence the phenotype of these mice and has to be taken into account in the interpretation of results regarding the functional role of DLG2 in neuronal postsynaptic membr... 29703139
2018-12-01 11:24:00 Study found robust hypersocial behavior in the dyadic interaction test in both PSD95(+/-) males and females. Additionally, male PSD95(+/-) mice exhibited higher levels of aggression and territoriality, while female PSD95(+/-) mice showed increased vocalization upon exposure to an anesthetized female mouse. Both male and female PSD95(+/-) mice revealed mild hypoactivity in the open field but no obvious motor deficit. 28189758

名称对应

Type IDs
Synonymous A330103J02Rik, B230218P12Rik, B330007M19Rik, Dlgh2, Gm1197, Gm21505, PSD93
Gene
UniProtKB-ID: DLG2_MOUSE, D3YWU0_MOUSE, A0A571BEZ4_MOUSE, D3YUZ8_MOUSE
UniprotKB: Q91XM9, D3YWU0, A0A571BEZ4, D3YUZ8
UniParc: UPI00002188B3, UPI00001F5AED, UPI000058BDEF, UPI0000DBED80, UPI0001F78AE2, UPI00027DB79B, UPI00027DB79A, UPI00002188B1, UPI0003D736D4, UPI00027DB799, UPI0001F78ACD
EMBL: AC108818, AC162304, AC101784, AC127299, AC108832, AC127683, AC161490, AC122002, AC118621, AC140196, AC100322, AC119218, AF388675, AC112262, AC121261, AK046525, AC141890, AC109506, AK039754
Ensembl: ENSMUSG00000052572
KO: mmu:23859
Nucleutide sequences
EMBL-CDS: BAC30440.1, AAK64496.1, BAC32772.1
Ensembl_TRS: ENSMUST00000238619, ENSMUST00000107196, ENSMUST00000098308, ENSMUST00000238467, ENSMUST00000107193
Protein sequencees
Ensembl_PRO: ENSMUSP00000158731, ENSMUSP00000102814, ENSMUSP00000095910, ENSMUSP00000158695, ENSMUSP00000102811
RefSeq: XP_036008932.1, XP_036008927.1, XP_006507848.1, XP_036008936.1, NP_001229976.1, XP_036008939.1, XP_036008944.1, XP_006507844.1, XP_036008924.1, XP_006507846.1, XP_030098403.1, XP_006507841.1, XP_006507832.1, XP_036008928.1, XP_036008929.1, XP_006507851.1, XP_006507836.1, XP_006507835.1, XP_036008943.1, XP_006507847.1, XP_030098402.1, XP_036008933.1, NP_035937.2, XP_036008942.1, XP_036008930.1, XP_036008925.1, XP_036008940.1, XP_006507834.1, XP_006507830.1, XP_006507853.1, XP_006507842.1, XP_006507850.1, XP_036008931.1, XP_036008935.1, XP_030098401.1, XP_006507852.1, XP_036008938.1, XP_006507839.1, XP_036008941.1, XP_036008934.1, XP_036008937.1, XP_006507840.1, XP_006507833.1, XP_006507845.1, XP_036008926.1, XP_006507843.1, XP_006507849.1, NP_001229975.1
Others
UniRef100: UniRef100_A0A571BEZ4, UniRef100_D3YUZ8, UniRef100_D3YWU0, UniRef100_Q91XM9
UniRef90: UniRef90_D3YWU0, UniRef90_D3YUZ8, UniRef90_Q91XM9, UniRef90_Q63622-4
UniRef50: UniRef50_Q63622-4, UniRef50_Q15700-3, UniRef50_D3YWU0, UniRef50_Q63622-7
UniGene: Mm.147213, Mm.257035
CCDS: CCDS40021.1

全选

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