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23831 Car14

23831

Car14

carbonic anhydrase 14

protein-coding

Mus musculus

基因描述

Type Description
Definition carbonic anhydrase 14

研究结论

Date Results Publications
2013-08-10 11:17:00 During inner ear development, transcripts of four cytosolic isozymes (Car1, Car2, Car3, and Car13), two membrane-bound isozymes (Car12 and Car14), and two CA-related proteins (Car8 and Car11) were expressed at higher levels than other isozymes. 23233153
2012-07-14 10:34:00 CAXIV functionally interacts with AE3, forming an extracellular membrane protein complex involved in the regulation of bicarbonate metabolism and pHi in the heart. 22227327
2010-01-21 00:00:00 CA XIV, which regulates extracellular pH and pCO(2), plays an important part in producing a normal retinal light response. 17485676
2010-01-21 00:00:00 CA XIV (along with carbonic anhydrase 4) plays an important role in the regulation of intracellular pH in hippocampus, via facilitation of anion exchanger AE3-mediated chloride-bicarbonate antiporter HCO3 exchange. 19279262
2010-01-21 00:00:00 studies on hippocampal slices on these KO mice showed that either CA can mediate buffering after synaptic transmission in hippocampal slices in the absence of the other, but that eliminating both is as effective in blocking the buffering seen in WT mice 16260723

名称对应

Type IDs
Synonymous AW536446, CA-XIV, Ca14
Gene
UniProtKB-ID: CAH14_MOUSE
UniprotKB: Q9WVT6
UniParc: UPI000000BB59
EMBL: BC046995, AB005450
Ensembl: ENSMUSG00000038526
KO: mmu:23831
Nucleutide sequences
EMBL-CDS: BAA78709.1, AAH46995.1
Ensembl_TRS: ENSMUST00000036181
Protein sequencees
Ensembl_PRO: ENSMUSP00000036983
RefSeq: NP_001342681.1, NP_001342680.1, XP_006501506.1, XP_006501505.1, NP_001342679.1, NP_035927.1
Others
UniRef100: UniRef100_Q9WVT6
UniRef90: UniRef90_Q9WVT6
UniRef50: UniRef50_Q9WVT6
UniGene: Mm.489647
CCDS: CCDS17625.1

全选

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