| Type | Description |
|---|---|
| Definition | ASH2 like histone lysine methyltransferase complex subunit |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:14:00 | Hematopoietic stem and progenitor cell proliferation and differentiation requires the trithorax protein Ash2l. | 31164666 |
| 2020-08-29 12:45:00 | The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. | 31315048 |
| 2019-12-14 10:50:00 | Transfection of Ash2l with W118A mutation to disrupt Ash2l-Oct4 interaction fails to rescue Ash2l-driven enhancer activation and pluripotent gene upregulation in Ash2l-depleted pluripotent stem cells. Together, our data demonstrated Ash2l formed an enhancer-bound Ash2l/OSN complex that can drive enhancer activation, govern pluripotency network and stemness circuitry. | 31555818 |
| 2019-09-21 10:49:00 | OCT4 directly activates expression of Ash2l-b. | 30269953 |
| 2018-07-07 11:23:00 | Ash2l-1 and Ash2l-2 are involved in the maintenance of mESCs pluripotency and the regulation of genomic H3K4me3. | 29576547 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
ASH2L_MOUSE,
E9PU93_MOUSE,
Q3UKZ9_MOUSE,
Q3UJ62_MOUSE
UniprotKB:
Q91X20,
E9PU93,
Q3UKZ9,
Q3UJ62
UniParc:
UPI00005AC589,
UPI0000EF892D,
UPI00000E88C3,
UPI00005AC442
EMBL:
AB020983,
BC012957,
AC122752,
AK145576,
AK146599,
AK145790,
AK087934,
AK146756,
AK145967,
AK146938
Ensembl:
ENSMUSG00000031575
KO:
mmu:23808
|
| Nucleutide sequences |
EMBL-CDS:
BAA35128.1,
BAC40047.1,
BAE27547.1,
AAH12957.1,
BAE27411.1,
BAE26792.1,
BAE26652.1,
BAE26521.1,
BAE27293.1
Ensembl_TRS:
ENSMUST00000068892,
ENSMUST00000110610,
ENSMUST00000110609,
ENSMUST00000166078
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000070957,
ENSMUSP00000132546,
ENSMUSP00000106240,
ENSMUSP00000106239
RefSeq:
XP_011240438.1,
NP_001345941.1,
NP_035921.2,
NP_001074262.1,
NP_001273136.1
|
| Others |
UniRef100:
UniRef100_Q91X20,
UniRef100_Q3UJ62
UniRef90:
UniRef90_Q9UBL3
UniRef50:
UniRef50_Q9UBL3
UniGene:
Mm.27706
CCDS:
CCDS40307.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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