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23805 Apc2

23805

Apc2

adenomatosis polyposis coli 2

protein-coding

Mus musculus

基因描述

Type Description
Definition adenomatosis polyposis coli 2

研究结论

Date Results Publications
2019-12-14 12:01:00 This work adds APC2 to the growing list of WNT-signalling members that regulate ovarian homeostasis, fertility and suppress granulosa cell tumour formation. 31291912
2018-10-27 12:05:00 Authors show that systemic loss of Apc2 results in an increase in the number of cells displaying nuclear beta-catenin at the base of the intestinal crypt. This subsequently impacts the expression levels of several ISC markers and the fitness of ISCs as assessed by organoid formation efficiency. 29027285
2012-07-07 11:57:00 Lack of adenomatosis polyposis coli 2 induces severe laminary defects in some regions of the mouse brain, including the cerebral cortex and cerebellum. 22573669
2011-04-16 11:09:00 This study provided genetic evidence that APC/C activity in the adult forebrain is required for cognitive function. 21191042
2010-01-21 00:00:00 Apc2 is expressed in post-mitotic cells and may contribute to the development of neuronal cells 15018807

名称对应

Type IDs
Synonymous AI852447, APCL, R75424
Gene
UniProtKB-ID: G5E832_MOUSE
UniprotKB: G5E832
UniParc: UPI00001E511D
EMBL: AC152062, AC140229
Ensembl: ENSMUSG00000020135
Nucleutide sequences
Ensembl_TRS: ENSMUST00000020349
Protein sequencees
Ensembl_PRO: ENSMUSP00000020349
RefSeq: NP_001359166.1, XP_006513709.1, NP_001359168.1, NP_001359170.1, NP_035919.2, NP_001359169.1, NP_001359167.1
Others
UniRef100: UniRef100_G5E832
UniRef90: UniRef90_Q9Z1K7
UniRef50: UniRef50_O95996
UniGene: Mm.57247

全选

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研究热度

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