| Type | Description |
|---|---|
| Definition | fascin actin-bundling protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-01-19 10:10:00 | These results demonstrate that, in C57BL/6Jmice, Fscn2 is essential for maintaining ear and eye function and that a null mutation of Fscn2 leads to progressive hearing loss and retinal degeneration. | 30082328 |
| 2018-01-06 10:41:00 | The results show that cross-talk through CD40-CD40L signaling drives elevated fascin expression in DCs to support acquisition of full T-cell responses. | 28369442 |
| 2016-05-14 11:47:00 | A quantitative trait locus on chromosome 5 modifies hearing loss associated with the fascin-2 variant of DBA/2J mice. | 26092689 |
| 2014-03-15 12:25:00 | Fascin and Daam1 coimmunoprecipitated from cell extracts, and silencing of fascin led to a striking loss of Daam1 localization to filopodial shafts. Purified fascin bound directly to Daam1; fascin recruited Daam1 to and stabilized Daam1 on actin bundles. | 23850281 |
| 2013-08-10 11:47:00 | The results of this study demonistrated that fascin-2 crosslinks function to slow actin depolymerization at stereocilia tips to maintain stereocilia length. | 23658152 |
| Type | IDs |
|---|---|
| Synonymous | A930022G03, Ahl8, C630046B20Rik |
| Gene |
UniProtKB-ID:
FSCN2_MOUSE
UniprotKB:
Q32M02
UniParc:
UPI00000225F2
EMBL:
BC109356,
BC109357,
AK050002,
AL669855,
CH466558
Ensembl:
ENSMUSG00000025380
KO:
mmu:238021
|
| Nucleutide sequences |
EMBL-CDS:
BAC34026.1,
EDL34739.1,
AAI09357.1,
AAI09358.1
Ensembl_TRS:
ENSMUST00000026445
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000026445
RefSeq:
NP_766390.2,
XP_006533322.1
|
| Others |
UniRef100:
UniRef100_Q32M02
UniRef90:
UniRef90_Q32M02
UniRef50:
UniRef50_Q32M02
UniGene:
Mm.481403
CCDS:
CCDS25731.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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