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237979 Sdk2

237979

Sdk2

sidekick cell adhesion molecule 2

protein-coding

Mus musculus

基因描述

Type Description
Definition sidekick cell adhesion molecule 2

研究结论

Date Results Publications
2018-10-06 10:24:00 The results suggest that the Ig-like domains and the fibronectin III (FnIII) domains of Sidekicks play different roles in cell adhesion. The Ig-like domains mediate the homophilic transinteractions bridging adjacent cells, while the FnIII domains interact with membranes, resulting in a tight adhesion interface between cells 30150416
2017-12-16 11:31:00 Here the authors report crystal structures of Sdk1 and Sdk2 ectodomain regions, revealing similar homodimers mediated by the four N-terminal immunoglobulin domains (Ig1-4), arranged in a horseshoe conformation. 27644106
2015-09-26 19:07:00 the Sdk2-specified synapse is essential for visual responses of W3B retinal ganglion cells 26287463
2010-04-12 12:17:00 These results demonstrate that localization and function of Sidekick-2 require its incorporation into a MAGI-containing synaptic scaffold. 20219992
2010-01-21 00:00:00 results establish that the first and second immunoglobulin domains of sidekick-1 and -2 are necessary and sufficient to mediate and target homophilic adhesion 15703275

名称对应

Type IDs
Synonymous 4632412F08Rik, 5330435L01Rik, Sdk-2, mKIAA1514
Gene
UniProtKB-ID: SDK2_MOUSE
UniprotKB: Q6V4S5
UniParc: UPI00005B1D24, UPI00001BDE0E, UPI00000273D3
EMBL: AK161326, AY351699, BC038036, AK129379
Ensembl: ENSMUSG00000041592
KO: mmu:237979
Nucleutide sequences
EMBL-CDS: AAH38036.1, BAC98189.1, AAQ57661.1, BAE36324.1
Ensembl_TRS: ENSMUST00000041627
Protein sequencees
Ensembl_PRO: ENSMUSP00000038972
RefSeq: NP_766388.2, XP_006533316.1, XP_006533317.1, XP_006533318.1
Others
UniRef100: UniRef100_Q6V4S5
UniRef90: UniRef90_Q6V4S5
UniRef50: UniRef50_Q6V4S5
UniGene: Mm.130504, Mm.401394
CCDS: CCDS25605.1

全选

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研究热度

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