| Type | Description |
|---|---|
| Definition | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:24:00 | Treatment of Dystrophic mdx Mice with an ADAMTS-5 Specific Increases the Ex Vivo Strength of Isolated Fast Twitch Hindlimb Muscles. | 32156081 |
| 2021-03-13 13:23:00 | Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican. | 32648916 |
| 2020-10-31 13:13:00 | Degrading products of chondroitin sulfate can induce hypertrophy-like changes and MMP-13/ADAMTS5 production in chondrocytes. | 31676809 |
| 2020-07-04 11:14:00 | Smo deletion mediates articular cartilage degeneration by ADAMTS-5 and Runx2 suppression | 31608494 |
| 2019-09-14 10:50:00 | In the absence of ADAMTS5, cleavage of versican in the cardiac extracellular matrix is impaired, but cardiac function, even upon exposure to a HFD, is not markedly affected. | 30958594 |
| Type | IDs |
|---|---|
| Synonymous | 9530092O11Rik, ADAM-TS5, ADAMTS1, ADAMTS11, ADMP-2, AI481094, ASMP-2 |
| Gene |
UniProtKB-ID:
ATS5_MOUSE,
Q8BGP4_MOUSE
UniprotKB:
Q9R001,
Q8BGP4
UniParc:
UPI00000EB9D5,
UPI000002203E
EMBL:
AK044746,
BC138620,
AF140673,
AK082475,
BC138619
Ensembl:
ENSMUSG00000022894
KO:
mmu:23794
|
| Nucleutide sequences |
EMBL-CDS:
AAI38621.1,
AAD56356.1,
AAI38620.1,
BAC38503.1,
BAC32062.1
Ensembl_TRS:
ENSMUST00000023611
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023611
RefSeq:
NP_035912.2,
XP_036015805.1
|
| Others |
UniRef100:
UniRef100_Q9R001
UniRef90:
UniRef90_Q9R001
UniRef50:
UniRef50_Q9UNA0
UniGene:
Mm.112933,
Mm.437478
CCDS:
CCDS28288.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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