| Type | Description |
|---|---|
| Definition | a disintegrin and metallopeptidase domain 23 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-08 10:18:00 | ADAM23 had a strong negative effect on the surface expression of Kv1.1 channels and on Kv1.1 current amplitude | 30965109 |
| 2019-11-09 11:46:00 | we identified ADAM23 as a negative regulator of cardiac hypertrophy through inhibiting focal adhesion kinase-protein kinase B signaling pathway, which could be a promising therapeutic target for this malady | 30371220 |
| 2017-09-16 12:20:00 | ADAM23 expression on DCs partially governs antigen-presentation capacities to responder CD4(+) T cells. Knockdown did not alter the maturation profile of DCs but impaired cognate T cell responses, decreased antigen-specific clonal expansion, and decreased Th cytokine production. Targeting the alpha(v)beta(3) integrin receptors resulted in similar phenotypes indicating their role in the ADAM23 response. | 27317750 |
| 2015-08-22 10:49:00 | Interaction proteomics revealed the interactors of Caspr2, including CNTN2, KCNAs, members of the ADAM family (ADAM22, ADAM23 and ADAM11), members of LGI family and MAGUKs (DLGs and MPPs). | 25707359 |
| 2013-04-27 11:51:00 | Adam23 knockdown up-regulates P27KIP1 in P19/ADAM23 knockdown cells, one reason that P19/ADAM23 knockdown cells can differentiate into neurons without retinoic acid induction. | 22973984 |
| Type | IDs |
|---|---|
| Synonymous | AW046396, MDC3 |
| Gene |
UniProtKB-ID:
ADA23_MOUSE
UniprotKB:
Q9R1V7
UniParc:
UPI00004704EE,
UPI0000022765,
UPI0000470EB3,
UPI0000470EB2
EMBL:
AL645637,
AL645534,
AK034022,
AY545641,
AL683801,
AB009673,
AY545640
Ensembl:
ENSMUSG00000025964
KO:
mmu:23792
|
| Nucleutide sequences |
EMBL-CDS:
BAA83381.1,
BAC28550.1,
AAS49901.1,
AAS49900.1
Ensembl_TRS:
ENSMUST00000114107,
ENSMUST00000087374,
ENSMUST00000114103
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000109742,
ENSMUSP00000139862,
ENSMUSP00000084633
RefSeq:
NP_035910.1,
XP_006496032.1,
XP_006496033.1
|
| Others |
UniRef100:
UniRef100_Q9R1V7
UniRef90:
UniRef90_Q9R1V7
UniRef50:
UniRef50_O75077
UniGene:
Mm.124892
CCDS:
CCDS14999.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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